STAGE IIB PANCREATIC CANCER AJCC V8

This early-phase trial tests a combination of two drugs, calaspargase pegol-mknl and cobimetinib, in 15 people with advanced or metastatic pancreatic cancer. The goal is to find the safest dose and see if the combo can shrink tumors by cutting off their nutrient supply. It is a s…

This study tests whether a combination of two drugs, lenvatinib and pembrolizumab, can help keep advanced pancreatic cancer from getting worse. The trial involves 28 adults whose cancer cannot be removed by surgery and who have already responded to initial treatment. The goal is …

This early-phase study tests whether adding losartan (a blood pressure medicine) to a shorter, higher-dose radiation treatment can help people with pancreatic cancer that is hard to remove surgically. The main goal is to check for side effects and find the safest dose. About 22 a…

This study tests a combination of two chemotherapy drugs and two immunotherapy drugs given before surgery to people with pancreatic cancer that can be removed. The goal is to shrink the tumor and help the immune system fight the cancer, potentially improving outcomes. The trial i…

This study tests a new method called sonoporation, which uses ultrasound and tiny gas bubbles to help chemotherapy drugs get into cancer cells more effectively. The trial includes 120 adults with advanced or hard-to-remove pancreatic cancer who are already receiving standard chem…