STAGE IIA BREAST CANCER
Clinical trials for STAGE IIA BREAST CANCER explained in plain language.
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New chemo combo shows promise for tough breast cancer
Disease control OngoingThis phase II trial tests whether giving two chemotherapy drugs, carboplatin and nab-paclitaxel, before surgery can improve outcomes for people with locally advanced or inflammatory triple negative breast cancer. The study aims to increase the rate of complete remission (no cance…
Matched conditions: STAGE IIA BREAST CANCER
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 22, 2026 11:58 UTC
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Could adding carboplatin beat triple-negative breast cancer?
Disease control OngoingThis study tests whether adding a drug called carboplatin to standard chemotherapy helps people with triple-negative breast cancer live longer without the cancer coming back. About 782 patients with high-risk or node-positive disease took part. The goal is to see if the stronger …
Matched conditions: STAGE IIA BREAST CANCER
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 18, 2026 11:49 UTC
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Immune booster before chemo shows promise for tough breast cancer
Disease control OngoingThis study tests whether giving two immunotherapy drugs (decitabine and pembrolizumab) before standard chemotherapy can help the immune system attack HER2-negative breast cancer more effectively. About 46 adults with locally advanced disease will receive a short course of these d…
Matched conditions: STAGE IIA BREAST CANCER
Phase: PHASE2 • Sponsor: Virginia Commonwealth University • Aim: Disease control
Last updated Jun 16, 2026 12:53 UTC
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New hope for tough breast cancer: which chemo works best after surgery?
Disease control OngoingThis study tests whether platinum-based chemotherapy (cisplatin or carboplatin) works better than capecitabine in people with a certain type of triple-negative breast cancer that remains after initial chemotherapy and surgery. About 415 participants with stage II-III breast cance…
Matched conditions: STAGE IIA BREAST CANCER
Phase: PHASE3 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated Jun 16, 2026 12:50 UTC
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Can adding a targeted drug shrink breast tumors before surgery?
Disease control OngoingThis study tests whether giving chemotherapy (paclitaxel and cyclophosphamide) with or without the targeted drug trastuzumab before surgery can shrink breast tumors and reduce the amount of tissue that needs to be removed. It includes 92 women with early-stage or locally advanced…
Matched conditions: STAGE IIA BREAST CANCER
Phase: PHASE2 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Jun 16, 2026 12:49 UTC
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Single dose of radiation during lumpectomy may control early breast cancer
Disease control OngoingThis study tests giving a single dose of radiation directly to the tumor site during breast-conserving surgery for early-stage breast cancer. The goal is to see if this one-time treatment works as well as standard radiation therapy that requires multiple visits. Over 1,200 partic…
Matched conditions: STAGE IIA BREAST CANCER
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 15, 2026 19:06 UTC
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Shorter radiation after mastectomy may cut side effects and prevent cancer return
Disease control OngoingThis study tests whether a shorter course of radiation (hypofractionated) after mastectomy works as well as standard radiation to keep breast cancer from coming back. About 900 people with stage II–III breast cancer who had a mastectomy and reconstruction took part. The shorter s…
Matched conditions: STAGE IIA BREAST CANCER
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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One-Time radiation boost during breast surgery shows promise in Early-Stage cancer trial
Disease control OngoingThis study tests whether giving a single dose of radiation directly to the tumor site during breast-conserving surgery (lumpectomy) and before reconstruction is safe and effective for women with early-stage breast cancer. About 108 participants with stage I-II breast cancer will …
Matched conditions: STAGE IIA BREAST CANCER
Phase: PHASE2 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 15, 2026 19:03 UTC