STAGE II RECTAL CANCER AJCC V8
Clinical trials for STAGE II RECTAL CANCER AJCC V8 explained in plain language.
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New trial tailors anal cancer treatment for people with HIV
Disease control OngoingThis phase 2 trial is testing whether adjusting treatment based on risk level can improve outcomes for people with HIV who have anal cancer. Low-risk patients receive standard chemotherapy and radiation, while high-risk patients also get the immunotherapy drug nivolumab after sta…
Matched conditions: STAGE II RECTAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 23, 2026 11:57 UTC
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Immunotherapy plus radiation may eliminate rectal cancer before surgery
Disease control OngoingThis study tests whether giving two immunotherapy drugs (nivolumab and ipilimumab) along with a short course of radiation can completely eliminate advanced rectal cancer before surgery. About 31 adults with a specific genetic type (MSI-H/dMMR) of stage II or III rectal cancer wil…
Matched conditions: STAGE II RECTAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 15, 2026 19:04 UTC
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New chemo cocktail may help rectal cancer patients skip surgery
Disease control OngoingThis study tests whether a three-drug chemotherapy combination (FOLFIRINOX) works better than the usual two-drug combinations (FOLFOX or CAPOX) after chemoradiation for patients with stage II-III rectal cancer. The goal is to achieve a clinical complete response, meaning no cance…
Matched conditions: STAGE II RECTAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 15, 2026 18:56 UTC
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Fasting during radiation may ease treatment side effects
Symptom relief OngoingThis study compares time-restricted eating (intermittent fasting) with standard nutritional counseling in cancer patients receiving radiation or chemoradiation for prostate, cervical, or rectal cancers. The goal is to see if fasting reduces treatment side effects and improves how…
Matched conditions: STAGE II RECTAL CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Jun 22, 2026 12:08 UTC
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Cancer treatment costs under the microscope: new study tracks financial toll
Knowledge-focused OngoingThis study follows 565 people with stage I-III colon or rectal cancer to understand how treatment affects their finances and quality of life. Participants complete surveys about costs and financial well-being over 12 months. The goal is to help doctors better support patients fac…
Matched conditions: STAGE II RECTAL CANCER AJCC V8
Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:51 UTC