SOLID TUMORS

This early-phase trial tested a new immunotherapy called BI 1821736 in 10 adults with advanced solid tumors that had not responded to standard treatments. BI 1821736 is a specially designed virus meant to kill cancer cells and help the immune system fight the cancer. Participants…

This early-phase study tested an experimental drug called INCB086550 in Japanese adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety and find the right dose. Only 3 people took part before the study was stopped…

This early-phase study tested an experimental drug called ABBV-303, alone or with another drug (budigalimab), in adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety and find the right dose. The study was termin…

This early-stage trial tested a combination of three drugs—azacitidine, pembrolizumab, and epacadostat—in 70 people with advanced solid tumors, including non-small cell lung cancer and colorectal cancer. The goal was to see if the combination was safe and could shrink tumors. How…

This early-phase study tested a new drug called LY3127804, given alone or with another drug (ramucirumab), in 62 people with advanced solid tumors. The main goal was to check safety and find the right dose. The study was stopped early, and the highest safe dose could not be deter…

This study tested a new cancer pill called BI 907828 in 99 adults with advanced bile duct, pancreas, lung, or bladder cancers that had stopped responding to other treatments. The drug works by blocking a protein called MDM2, which helps some cancers grow. Participants took the pi…

This early-stage study tested a new drug called INCB062079 in 25 people with advanced liver cancer or other solid tumors that had spread. The main goal was to check the drug's safety and find the best dose. The study was stopped early, so results are limited.

This study tested a new drug, PF-08046031, in 11 adults with advanced melanoma or other solid tumors that had spread or had no standard treatment. The goal was to check safety and side effects, and to find the right dose. The trial was terminated early, so results are limited.

This study tested an experimental drug called INCB057643 in 137 people with advanced cancers that had stopped responding to standard treatments. The goal was to find a safe dose and check for side effects, both when given alone and with other cancer drugs. The trial was terminate…

This early-phase study tested a new drug called eciskafusp alfa, alone or with another immunotherapy (atezolizumab), in 189 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety and find the right dose. The study…

This study looked at how adults with advanced or metastatic solid tumors absorb, break down, and remove the drug subasumstat. Only 3 people took part, and the study was stopped early. The goal was to measure the drug in urine and stool, not to test if it works as a treatment.