SMALL LYMPHOCYTIC LYMPHOMA (SLL)
Clinical trials for SMALL LYMPHOCYTIC LYMPHOMA (SLL) explained in plain language.
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New hope for Tough-to-Treat leukemia: experimental drug NX-5948 enters phase 2
Disease control Recruiting nowThis study tests an experimental drug called NX-5948 in about 100 adults whose chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) has returned or stopped responding to standard treatments. Participants must have already tried both a BTK inhibitor and a BCL-2 i…
Matched conditions: SMALL LYMPHOCYTIC LYMPHOMA (SLL)
Phase: PHASE2 • Sponsor: Nurix Therapeutics, Inc. • Aim: Disease control
Last updated May 26, 2026 04:49 UTC
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New hope for Hard-to-Treat blood cancers: venetoclax trial underway
Disease control Recruiting nowThis study tests the drug venetoclax in people with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) that has come back or not responded to other treatments. About 110 participants will receive venetoclax to see if it shrinks or controls their cancer. The go…
Matched conditions: SMALL LYMPHOCYTIC LYMPHOMA (SLL)
Phase: PHASE2 • Sponsor: AbbVie • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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New drug targets Hard-to-Treat blood cancers in early trial
Disease control Recruiting nowThis early-stage study tests a new drug called NX-2127 in adults with certain blood cancers (like CLL or lymphoma) that have returned or not improved after other treatments. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. About …
Matched conditions: SMALL LYMPHOCYTIC LYMPHOMA (SLL)
Phase: PHASE1 • Sponsor: Nurix Therapeutics, Inc. • Aim: Disease control
Last updated May 18, 2026 12:11 UTC
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New drug targets Hard-to-Treat blood cancers in early trial
Disease control Recruiting nowThis study tests an experimental drug called NX-5948 in adults with certain blood cancers (like CLL or lymphoma) that have come back or stopped responding to treatment. The drug works by breaking down a protein that helps cancer cells grow. The main goals are to find a safe dose …
Matched conditions: SMALL LYMPHOCYTIC LYMPHOMA (SLL)
Phase: PHASE1 • Sponsor: Nurix Therapeutics, Inc. • Aim: Disease control
Last updated May 18, 2026 12:09 UTC
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New triple therapy aims to wipe out CLL cells in untreated patients
Disease control Recruiting nowThis study tests a combination of three drugs (zanubrutinib, obinutuzumab, and sonrotoclax) in people with untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The main goal is to see if the treatment can make the cancer undetectable in the blood. Abo…
Matched conditions: SMALL LYMPHOCYTIC LYMPHOMA (SLL)
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated May 18, 2026 12:02 UTC
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New drug combo aims to deeply suppress blood cancer in relapsed patients
Disease control Recruiting nowThis study tests whether combining two targeted drugs, zanubrutinib and venetoclax, can deeply suppress chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) in people whose cancer returned after prior treatment. About 45 adults who have not used these specific d…
Matched conditions: SMALL LYMPHOCYTIC LYMPHOMA (SLL)
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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New study probes immune effects of First-Line CLL drug
Knowledge-focused Recruiting nowThis early-phase study looks at how the drug pirtobrutinib changes immune cells in people with untreated chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). Researchers will enroll 30 adults to take pirtobrutinib daily and will analyze blood and lymph node sam…
Matched conditions: SMALL LYMPHOCYTIC LYMPHOMA (SLL)
Phase: EARLY_PHASE1 • Sponsor: National Heart, Lung, and Blood Institute (NHLBI) • Aim: Knowledge-focused
Last updated May 26, 2026 04:54 UTC
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New study tracks daily life changes in leukemia patients on modern therapies
Knowledge-focused Recruiting nowThis study follows 100 adults with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) for 2 years to see how their quality of life, fatigue, and symptoms change after starting treatment. Researchers compare two common drug types to help future patients know wh…
Matched conditions: SMALL LYMPHOCYTIC LYMPHOMA (SLL)
Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC