SLE - SYSTEMIC LUPUS ERYTHEMATOSUS
Clinical trials for SLE - SYSTEMIC LUPUS ERYTHEMATOSUS explained in plain language.
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Experimental CAR T-Cell therapy aims to tame lupus kidney disease
Disease control Not yet recruitingThis phase 2 trial tests a single infusion of FT819, a CAR T-cell therapy made from donor cells, in 53 people with moderate-to-severe lupus nephritis that hasn't responded to other treatments. The goal is to see if it can improve kidney function and reduce disease activity. Parti…
Matched conditions: SLE - SYSTEMIC LUPUS ERYTHEMATOSUS
Phase: PHASE2 • Sponsor: Fate Therapeutics • Aim: Disease control
Last updated Jun 23, 2026 23:32 UTC
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New lupus drug candidate enters human safety testing
Disease control Not yet recruitingThis early-stage study tests a new drug called IASO-782 in 20 adults with systemic lupus erythematosus (SLE). The main goal is to see if the drug is safe and tolerable. Participants will receive either the drug or a placebo, and researchers will monitor for side effects.
Matched conditions: SLE - SYSTEMIC LUPUS ERYTHEMATOSUS
Phase: PHASE1 • Sponsor: Shanghai IASO Biotechnology Co., Ltd • Aim: Disease control
Last updated Jun 15, 2026 19:08 UTC
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Engineered immune cells take on lupus in early trial
Disease control Not yet recruitingThis early-phase study tests a new treatment called CD19/BCMA CAR-T cell therapy for adults with refractory systemic lupus erythematosus (SLE) that hasn't improved with standard treatments. About 24 participants will receive a single infusion of their own engineered immune cells …
Matched conditions: SLE - SYSTEMIC LUPUS ERYTHEMATOSUS
Phase: EARLY_PHASE1 • Sponsor: Chengdu Ucello Biotechnology Co., Ltd. • Aim: Disease control
Last updated Jun 15, 2026 19:07 UTC
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Off-the-Shelf CAR-Ts take on lupus and more
Disease control Not yet recruitingThis early-phase trial tests a single dose of universal (off-the-shelf) CAR-T cells in 30 adults with active autoimmune diseases like lupus, scleroderma, vasculitis, myositis, or Sjögren's. The treatment targets CD19 and BCMA on immune cells to reset the faulty immune system. The…
Matched conditions: SLE - SYSTEMIC LUPUS ERYTHEMATOSUS
Phase: EARLY_PHASE1 • Sponsor: Nanjing Bioheng Biotech Co., Ltd. • Aim: Disease control
Last updated Jun 12, 2026 12:04 UTC
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Could a common stomach bug worsen lupus? new study aims to find out
Knowledge-focused Not yet recruitingThis study will check 115 adults with lupus for H. pylori infection using a stool test. Researchers will then compare disease activity between those with and without the infection. The goal is to see if there is a link, which could lead to better management of lupus.
Matched conditions: SLE - SYSTEMIC LUPUS ERYTHEMATOSUS
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:56 UTC