SKIN DISEASES

This study tests a gel called Oleogel-S10 on skin wounds in Japanese children and adults with two types of epidermolysis bullosa (EB), a genetic condition causing fragile skin. The main goal is to see if the gel can close wounds within 45 days and check for any side effects. Part…

This study tests whether baricitinib, a daily pill, can safely help children aged 6 to 17 with severe alopecia areata (patchy hair loss) regrow their hair. About 595 kids will receive either the drug or a placebo for 36 weeks, then all can get the drug for up to 2 years. The main…

This study follows 200 people aged 12 and older with moderate-to-severe eczema who are starting a new prescription of abrocitinib. Researchers will track how much their skin improves over 12 months in real-world settings, not a controlled lab. The goal is to see how well the drug…

This study tests whether the drug guselkumab can heal painful skin ulcers in people with pyoderma gangrenosum. Seventeen adults with at least one ulcer will receive the drug and be checked at weeks 6, 16, and 32. The main goal is to see if the ulcer fully closes by week 32.

This early-stage study tests a new drug called BG-A3004 for safety and how the body processes it. It includes healthy volunteers and people with immune-related skin conditions. Participants receive either the drug or a placebo, and researchers monitor side effects and drug levels…

This study tests whether dupilumab, a drug already used for eczema, can reduce severe itching in people with genetic skin disorders. About 30 participants will receive the drug for up to 104 weeks. The goal is to see if itch improves and if the treatment is safe.

This study collects anonymous symptom descriptions from 1,000 adults through the OpenGenome website. An AI then searches medical databases to see if it can correctly match symptoms to scientific evidence. No treatment or follow-up is provided. The goal is to improve how symptoms …

This study aims to create a large collection of blood samples and medical data from 800 people with autoimmune or inflammatory skin diseases. Researchers will use these samples to discover new biomarkers and better understand what causes these conditions. The goal is to help scie…

This study tracks 500 adults starting their first chemotherapy through a chest port. The goal is to measure how often skin reactions like itching or redness happen at the dressing site. Researchers will also look for factors that raise the risk of these reactions, such as the typ…

This study is testing a new imaging tool called OCT Vibrography that measures how stiff or flexible tissues like the cornea, skin, and gums are. About 90 healthy volunteers will have their tissues scanned with a special light-based device. The goal is to see if the tool is safe a…

This study aims to find biological markers (biomarkers) that can help doctors better diagnose and monitor chronic induced urticaria (CIndU), a condition where specific triggers like cold or pressure cause itchy hives or swelling. Researchers will compare 40 participants—including…

This study looks at how treatments for eczema (atopic dermatitis) change the types and amounts of bacteria on the skin. Researchers will compare skin samples from people with eczema and healthy volunteers over one year. The goal is to understand how treatments affect the skin's m…