SJOGREN'S SYNDROME

This study tested whether baricitinib, a drug that calms the immune system, can help people with active Sjogren's syndrome. About 87 adults were randomly assigned to receive either standard care (hydroxychloroquine) or baricitinib with or without hydroxychloroquine for 24 weeks. …

This study tested an experimental drug called SAR441344 in 84 adults with primary Sjögren's syndrome, an autoimmune disease causing dry eyes, dry mouth, and fatigue. The goal was to see if the drug could reduce disease activity and improve symptoms over 12 weeks compared to a pla…

This study looked at the safety of a drug called iscalimab in 206 people with Sjögren's syndrome, an autoimmune disease that causes dry eyes and mouth. Participants had already completed a previous study and received iscalimab injections at two different doses. The main goal was …

This study tested an artificial intelligence (AI) program designed to help doctors diagnose Sjogren's syndrome. The AI analyzes images of minor salivary gland biopsies to count immune cells, a key sign of the disease. Researchers compared the AI's results to those of expert patho…

This study looked at whether regular aerobic exercise can reduce fatigue in women with primary Sjögren's syndrome, a condition that causes dryness and extreme tiredness. Forty-five women took part in a 16-week exercise program. Researchers measured changes in fatigue, mood, quali…

This small pilot study tested whether levocarnitine, a natural substance, can help relieve dry eye in adults with Sjogren's syndrome. Fifteen participants received both the supplement and a placebo at different times to compare effects. The goal was to see if it reduces eye infla…

This study looked at whether removing wheat from the diet can reduce symptoms like pain, fatigue, and dryness in people with Sjogren's syndrome. Thirty adults with Sjogren's followed a wheat-free diet for a period, and researchers measured changes in their symptoms and inflammati…

This study looked at whether immune cells from the intestine play a role in Sjogren's syndrome, an autoimmune disease that causes dry eyes and mouth. Researchers examined saliva gland samples from 57 adults suspected of having Sjogren's. The goal was to better understand the dise…

This study looked at how often people with primary Sjögren's syndrome have digestive issues. Researchers used a questionnaire to track 10 different digestive symptoms in 151 patients. The goal was to better understand these symptoms and how they relate to the disease.