SIGNS AND SYMPTOMS
Clinical trials for SIGNS AND SYMPTOMS explained in plain language.
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New dissolving heart scaffold could replace permanent stents
Disease control Not yet recruitingThis study compares a new device called Freesolve, a temporary magnesium scaffold that dissolves over time, to a standard permanent metal stent for treating blocked heart arteries. About 1,859 people with coronary artery disease will be enrolled to see if the dissolving scaffold …
Matched conditions: SIGNS AND SYMPTOMS
Phase: NA • Sponsor: Teleflex • Aim: Disease control
Last updated May 19, 2026 12:01 UTC
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Migraine mystery: does amylin spark attacks?
Knowledge-focused Not yet recruitingThis study looks at whether a drug called pramlintide, which mimics a natural body chemical (amylin), can cause migraine attacks in people who get migraines without aura. About 21 adults with a history of migraine without aura will receive either pramlintide or a placebo, and res…
Matched conditions: SIGNS AND SYMPTOMS
Phase: NA • Sponsor: Danish Headache Center • Aim: Knowledge-focused
Last updated May 26, 2026 04:32 UTC
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Scientists investigate whether a diabetes drug can spark headaches in brain injury survivors
Knowledge-focused Not yet recruitingThis study looks at whether pramlintide, a substance similar to a natural hormone, can cause migraine-like headaches in people who have had persistent headaches for at least a year after a mild traumatic brain injury. About 21 adults aged 18 to 65 will receive either pramlintide …
Matched conditions: SIGNS AND SYMPTOMS
Phase: NA • Sponsor: Danish Headache Center • Aim: Knowledge-focused
Last updated May 18, 2026 12:12 UTC
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Migraine mystery: new study probes Adrenomedullin's role
Knowledge-focused Not yet recruitingThis study looks at whether a natural brain chemical called adrenomedullin can cause migraine attacks in people who already get migraines. Researchers will give the chemical to 26 adults with migraine without aura, after they have taken a preventive migraine drug (erenumab). The …
Matched conditions: SIGNS AND SYMPTOMS
Phase: NA • Sponsor: Danish Headache Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC