SENSORINEURAL HEARING LOSS, BILATERAL

This study tests a gene therapy for people with severe hearing loss caused by otoferlin gene mutations. The treatment delivers a working copy of the gene into the inner ear during a single surgery. Up to 22 participants of any age will be enrolled to check safety and whether hear…

This study tests whether a new method of adjusting hearing aids and cochlear implants (called tonotopy-based fitting) helps people understand speech better in noisy environments compared to the standard method. About 20 adults with hearing loss in both ears who are getting a coch…

This study tests whether synchronizing a hearing aid with a cochlear implant helps people with hearing loss locate sounds better than using them without synchronization. Twenty adults who are new cochlear implant users will try both methods and compare results. The goal is to imp…

This study tests two different methods for adjusting cochlear implants to see which one helps adults with hearing loss understand speech better in noisy environments. About 22 French-speaking adults who have had a MED-EL cochlear implant for at least 6 months will try both tuning…

This study tests a new way to program cochlear implants (called tonotopic fitting) to see if it helps adults with hearing loss understand speech better in noisy places. Twenty-five French-speaking adults who have had a cochlear implant for six months will compare the new setting …

This study follows up to 180 children with hearing loss caused by mutations in the GJB2 or OTOF genes. Researchers will measure hearing and auditory responses over time to understand how the condition naturally progresses. No treatment is given; the goal is to gather information …

This study follows up to 150 people with hearing loss caused by changes in the otoferlin gene. Researchers will measure hearing using tests like auditory brainstem response (ABR) and otoacoustic emissions (OAE) over time. The goal is to better understand how this type of hearing …

This study looks at whether stimulating deeper parts of the inner ear with a MED-EL cochlear implant helps adults with hearing loss perceive music better. About 32 French-speaking adults who already qualify for a cochlear implant will take part. Researchers will compare standard …

This study aims to learn how hearing loss changes over time in adults aged 30 to 55 who have a specific genetic change (in the GJB2 gene) and first noticed hearing problems after age 16. Researchers will measure hearing with standard tests and also look at mood and genetic detail…