SARS-CoV infection
Clinical trials for SARS-CoV infection explained in plain language.
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Can an oral drug stop COVID-19 from turning deadly?
Disease control CompletedResearchers are testing an experimental oral drug called sabizabulin (VERU-111) in hospitalized adults with confirmed SARS-CoV-2 infection who are at high risk for acute respiratory distress syndrome (ARDS). Participants receive either sabizabulin plus standard care or a placebo …
Matched conditions: SARS-COV INFECTION
Phase 3 • Sponsor: Veru Inc. • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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Cheap diabetes drug metformin slashes long COVID risk in major trial
Disease control CompletedThis study tested whether three common drugs—metformin, ivermectin, and fluvoxamine—could prevent severe illness and long COVID in 1,323 adults with early COVID-19. Participants were overweight or obese and not hospitalized. The key finding was that metformin reduced the risk of …
Matched conditions: SARS-COV INFECTION
Phase 3 • Sponsor: University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New pill may stop COVID-19 after exposure – trial underway
Prevention CompletedThis study tests whether a pill called mitoquinone can prevent COVID-19 in healthy adults who have had close contact with someone who has COVID-19. About 112 participants will receive either the pill or a placebo. The goal is to see if it stops infection and reduces symptoms.
Matched conditions: SARS-COV INFECTION
Phase 2 • Sponsor: University of Texas Southwestern Medical Center • Aim: Prevention
Last updated Sep 21, 2026 17:00 UTC
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New study tracks COVID vaccine durability in chronic illness patients
Knowledge-focused CompletedThis completed study followed 360 adults and children with chronic respiratory and other medical conditions to see how their immune systems responded to COVID-19 vaccines over 18 months. Researchers measured antibody, T cell, and B cell levels before vaccination and every 3 month…
Matched conditions: SARS-COV INFECTION
Sponsor: National Jewish Health • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC