SAFETY

This study is checking the safety of the Prevenar 20 vaccine after it is already available in Korea. About 660 people aged 6 weeks and older who are prescribed the vaccine will take part. Researchers will track any side effects for 28 days after the shot.

This study tests a new drug, HY07121, in 258 adults with advanced solid tumors that have not responded to standard treatments. The goal is to see if the drug is safe, tolerable, and can shrink tumors. Participants receive the drug by infusion, and the study will monitor side effe…

This early-stage study tests whether a single injection of lab-grown nerve cells (made from stem cells) is safe for people with a recent spinal cord injury. The cells are designed to replace damaged nerve connections. The trial involves 12 adults with injuries between the neck an…

This study tests an experimental drug called HYP-2090PTSA in people with advanced solid tumors that have a KRAS mutation. The goal is to find a safe dose and see if the drug can shrink tumors. About 257 adults will take part in two phases: first to check safety, then to measure e…

This study tests whether adding the experimental drug AK104 to standard chemotherapy and either cetuximab or bevacizumab can shrink tumors in people with a specific type of advanced colorectal cancer (MSS type) that has spread. About 40 adults aged 18 to 75 whose cancer got worse…

This early-phase study tests whether stem cells from amniotic fluid can help heal painful skin wounds (calciphylaxis) in people with chronic kidney disease. Nine participants will receive the stem cell treatment, and researchers will measure wound healing and pain levels. The goa…

This early-stage study tests whether a new medicine called GenSci134 is safe and tolerable for people. It involves healthy adults and patients with adult growth hormone deficiency, a condition where the body doesn't make enough growth hormone. Participants receive either the stud…

This early-stage study tests a single injection of a new drug called GenSci098 in 24 adults with Graves' disease, a condition where the thyroid is overactive. The main goal is to see if the drug is safe and what side effects it might cause. Participants must have stopped other th…

This early-stage study tests the safety of a new drug called GenSci098 in 76 adults with active thyroid eye disease (TED). Participants receive one or more injections under the skin, and researchers monitor for side effects and how the drug moves through the body. The goal is to …

This study tests an experimental drug called IRL757 in 75 people with Parkinson's disease who also have apathy (loss of interest or motivation). The main goal is to check if the drug is safe and tolerable over 12 weeks. Researchers will also see if it helps improve apathy symptom…

This early-stage study tests whether psilocybin (the active ingredient in magic mushrooms) combined with talk therapy can safely reduce feelings of hopelessness and loss of meaning in people with advanced cancer. Fifteen adults aged 18-70 with stage 3 or 4 cancer and high demoral…

This study tests the long-term safety of a supplement called palmitoylethanolamide (PEA) in 200 healthy adults aged 18 and older. Participants take either PEA or a placebo daily for 12 months and attend check-ups to monitor side effects, vital signs, and blood work. The goal is s…

This early-stage study tests whether a single inhaled dose of RCS-21 is safe and tolerable in 24 healthy adults aged 18 to 64. Participants receive one dose and are closely monitored for side effects. The study does not aim to treat any disease, but to gather important safety and…

This study surveys 400 doctors, nurses, and respiratory therapists worldwide to understand how non-invasive ventilation (breathing support via mask or helmet) is used outside intensive care units. The goal is to identify current practices, outcomes, and barriers to guide safer an…

This early-phase study tests whether taking curcumin (a compound in turmeric) for two weeks can cross into the brain and attach to amyloid-beta proteins, which are linked to Alzheimer's disease. Researchers will use special eye imaging to see if these proteins show up in the reti…

This early-stage study tests a new antibiotic combination (ceftibuten-ledaborbactam etzadroxil) in about 46 healthy adults aged 18-55. The goal is to check safety and how the drug moves through the body, not to treat any disease. Results will help decide if further studies are po…