Rheumatic heart disease
Clinical trials for Rheumatic heart disease explained in plain language.
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Can two existing drugs stop rheumatic fever from scarring young hearts?
Disease control Not yet recruitingResearchers are running a Phase 3 trial to see whether hydroxychloroquine or corticosteroids can reduce heart valve damage in children and young people with acute rheumatic fever. The trial enrolls about 600 participants aged 4 to 25 who are hospitalized with confirmed valve infl…
Matched conditions: RHEUMATIC HEART DISEASE
Phase 3 • Sponsor: Starship Child Health, Te Toka Tumai Auckland • Aim: Disease control
Last updated Sep 21, 2026 22:00 UTC
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Could a monthly pill replace painful penicillin shots for rheumatic heart disease?
Disease control Not yet recruitingThis study will test if taking oral azithromycin pills for three days each month works as well as getting a monthly penicillin shot to prevent rheumatic heart disease from getting worse. The trial plans to enroll 474 Nigerian secondary school students aged 10-18 with mild or mode…
Matched conditions: RHEUMATIC HEART DISEASE
Sponsor: Ladoke Akintola University of Technology, Ogbomoso, Nigeria • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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AI could revolutionize heart disease screening in poor regions
Diagnosis Not yet recruitingThis study tests whether an AI tool called RADAR can help nurses in low-resource settings detect rheumatic heart disease more accurately using echocardiography. The goal is to make screening easier to scale up worldwide. The trial will enroll 62 nurse screeners at participating f…
Matched conditions: RHEUMATIC HEART DISEASE
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Diagnosis
Last updated Jun 27, 2026 12:38 UTC
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The clotting test that could reshape warfarin care in egypt
Knowledge-focused Not yet recruitingPeople with rheumatic heart disease and atrial fibrillation take warfarin to prevent strokes, but the drug only works safely when blood clotting stays in a narrow target range. Researchers at Assiut University are studying about 90 Egyptian adults on warfarin for at least six mon…
Matched conditions: RHEUMATIC HEART DISEASE
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Sep 19, 2026 00:00 UTC
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New registry tool aims to stop heart patients from falling through the cracks
Knowledge-focused Not yet recruitingThis study tests a cloud-based tool called ACT+ to help people in Uganda get follow-up care after a positive screening for rheumatic heart disease. Researchers will work with local providers to improve the tool and then see if it increases the number of people who complete a conf…
Matched conditions: RHEUMATIC HEART DISEASE
Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated Jul 15, 2026 00:00 UTC