RESTLESS LEG SYNDROME (RLS)
Clinical trials for RESTLESS LEG SYNDROME (RLS) explained in plain language.
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Cannabis put to the test for restless legs relief
Symptom relief Recruiting nowThis study tests whether cannabis is safe and practical for treating restless legs syndrome (RLS), a condition causing painful leg sensations and poor sleep. Thirty adults with moderate-to-severe RLS will receive either cannabis or a placebo for 8 weeks. Researchers will track si…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated May 26, 2026 12:09 UTC
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Could a simple nerve zap ease restless legs in pregnancy?
Symptom relief Recruiting nowThis study is testing whether a small, non-invasive device that stimulates a nerve in the leg can safely and effectively relieve Restless Legs Syndrome (RLS) in pregnant women. Fifteen participants between 21 and 26 weeks pregnant will use the TOMAC™ device for 30-minute sessions…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: NA • Sponsor: Rhode Island Hospital • Aim: Symptom relief
Last updated May 18, 2026 12:03 UTC
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New pill could calm restless legs in early trial
Symptom relief Recruiting nowThis early-stage study is testing a new medication for Restless Legs Syndrome (RLS), a condition that causes uncomfortable urges to move the legs. About 20 adults with moderate to severe RLS will take the drug twice daily for 12 weeks. Researchers will measure changes in symptom …
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: PHASE1 • Sponsor: Beijing Friendship Hospital • Aim: Symptom relief
Last updated May 14, 2026 12:05 UTC
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RLS drug study seeks clues in your nose
Knowledge-focused Recruiting nowThis study looks at how using dopamine agonist drugs for a long time changes gene activity in people with Restless Legs Syndrome (RLS). Researchers will collect nasal swabs from 50 adults who are either new to these medications or have taken them for 6 months or more. The goal is…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Sponsor: HBC Immunology Inc • Aim: Knowledge-focused
Last updated May 20, 2026 11:53 UTC
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Spinal cord zaps may soothe restless legs – new study launches
Knowledge-focused Recruiting nowThis study looks at how spinal cord stimulators change nerve signals and symptoms in people with restless leg syndrome (RLS) and chronic pain. Researchers will use brain and nerve tests to measure these changes. The study includes 50 adults with RLS, chronic pain, or both, and ai…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated May 18, 2026 12:11 UTC