RESTLESS LEG SYNDROME (RLS)
Clinical trials for RESTLESS LEG SYNDROME (RLS) explained in plain language.
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Could a simple nerve zap soothe restless legs in pregnancy?
Symptom relief Recruiting nowThis study tests a small, non-invasive device that stimulates a nerve in the leg to see if it can safely ease Restless Legs Syndrome (RLS) during pregnancy. Fifteen pregnant women between 21 and 26 weeks will use the device for 30-minute sessions over 8 weeks. Researchers will ch…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: NA • Sponsor: Rhode Island Hospital • Aim: Symptom relief
Last updated Jun 22, 2026 12:03 UTC
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Can cannabis calm restless legs? new study aims to find out
Symptom relief Recruiting nowThis pilot study will test whether cannabis oil can safely help people with restless legs syndrome (RLS). Thirty adults with moderate-to-severe RLS will receive either cannabis oil or a placebo for 8 weeks. Researchers will track side effects, how many people finish the study, an…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Jun 22, 2026 11:57 UTC
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New pill could quiet restless legs – early trial underway
Symptom relief Recruiting nowThis early-stage study is testing a new calcium channel modulator to see if it can ease symptoms of Restless Legs Syndrome (RLS). About 20 adults with moderate-to-severe RLS will take the drug twice a day for 12 weeks. Researchers will measure changes in symptom severity and watc…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: PHASE1 • Sponsor: Beijing Friendship Hospital • Aim: Symptom relief
Last updated Jun 16, 2026 12:48 UTC
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Spinal cord zaps tested for restless legs: hope or hype?
Knowledge-focused Recruiting nowThis study looks at how spinal cord stimulators change nerve signals and symptoms in people with Restless Leg Syndrome. Researchers will measure brain and muscle activity in 50 participants, including those with and without the condition. The goal is to understand how the stimula…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 18, 2026 11:49 UTC
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RLS drug study probes genetic changes behind worsening symptoms
Knowledge-focused Recruiting nowThis study looks at how taking certain RLS medications for a long time may change the activity of genes related to dopamine. Researchers will collect nasal swabs from 50 adults with RLS who have either just started or been on these drugs for 6+ months. The goal is to understand w…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Sponsor: HBC Immunology Inc • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:27 UTC