RESTLESS LEG SYNDROME (RLS)
Clinical trials for RESTLESS LEG SYNDROME (RLS) explained in plain language.
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New pill could quiet restless legs – early trial underway
Symptom relief Recruiting nowThis early-stage study is testing a new calcium channel modulator to see if it can ease symptoms of Restless Legs Syndrome (RLS). About 20 adults with moderate-to-severe RLS will take the drug twice a day for 12 weeks. Researchers will measure changes in symptom severity and watc…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: PHASE1 • Sponsor: Beijing Friendship Hospital • Aim: Symptom relief
Last updated Jun 16, 2026 12:48 UTC
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Can cannabis calm restless legs? new study seeks answers
Symptom relief Recruiting nowThis study tests whether cannabis is safe and practical for treating restless legs syndrome (RLS), a condition causing uncomfortable leg sensations and poor sleep. Thirty adults with moderate-to-severe RLS will receive either cannabis or a placebo for 8 weeks. Researchers will mo…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: NA • Sponsor: Sunnybrook Health Sciences Centre • Aim: Symptom relief
Last updated Jun 11, 2026 12:12 UTC
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Could a simple nerve zap ease restless legs in pregnancy?
Symptom relief Recruiting nowThis small study is testing whether a non-invasive nerve stimulation device (TOMAC™) can safely and effectively relieve Restless Legs Syndrome (RLS) in pregnant women. Fifteen pregnant participants between 21 and 26 weeks will use the device for 30-minute sessions as needed over …
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: NA • Sponsor: Rhode Island Hospital • Aim: Symptom relief
Last updated Jun 11, 2026 12:11 UTC
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Spinal cord stimulators tested for restless leg relief
Knowledge-focused Recruiting nowThis study looks at how spinal cord stimulators (SCS) change nerve signals and symptoms in people with restless leg syndrome (RLS). Researchers will measure brain and muscle activity using tests like EEG and EMG while the stimulator is on or off. The goal is to understand how SCS…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Phase: NA • Sponsor: University of Alabama at Birmingham • Aim: Knowledge-focused
Last updated Jun 15, 2026 18:57 UTC
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RLS drug study probes genetic changes behind worsening symptoms
Knowledge-focused Recruiting nowThis study looks at how taking certain RLS medications for a long time may change the activity of genes related to dopamine. Researchers will collect nasal swabs from 50 adults with RLS who have either just started or been on these drugs for 6+ months. The goal is to understand w…
Matched conditions: RESTLESS LEG SYNDROME (RLS)
Sponsor: HBC Immunology Inc • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:27 UTC