RLS drug study probes genetic changes behind worsening symptoms

NCT ID NCT06726785

First seen Nov 01, 2025 · Last updated Jun 10, 2026 · Updated 37 times

Summary

This study looks at how taking certain RLS medications for a long time may change the activity of genes related to dopamine. Researchers will collect nasal swabs from 50 adults with RLS who have either just started or been on these drugs for 6+ months. The goal is to understand why some people develop worsening symptoms, called augmentation, after prolonged use.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alethios Inc

    RECRUITING

    San Francisco, California, 94109, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.