Refractory solid tumor
Clinical trials for Refractory solid tumor explained in plain language.
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Personalized dosing of cancer drug pazopanib tested in early trial
Disease control OngoingThis phase I trial tests the drug pazopanib (Votrient) in 54 patients with advanced solid tumors that have spread or not responded to other treatments. Pazopanib works by blocking blood vessel growth that tumors need. Researchers aim to find the best dose that balances effectiven…
Matched conditions: REFRACTORY SOLID TUMOR
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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New pill takes on tough cancers in first human test
Disease control OngoingThis early-stage trial tests an experimental oral drug called CID-078 in 220 adults with advanced solid tumors that have not responded to standard treatments. The study is split into two parts: first, finding a safe dose, and then checking if the drug shrinks tumors. It is a firs…
Matched conditions: REFRACTORY SOLID TUMOR
Phase 1 • Sponsor: Circle Pharma • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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New hope for kids with tough cancers: SGT-53 drug trial launches
Disease control PausedThis early-stage study tests a new drug called SGT-53, given alone or with chemotherapy, in children and young adults (ages 1-21) with solid tumors that have come back or not responded to treatment. The main goals are to find safe doses and understand side effects. The study is c…
Matched conditions: REFRACTORY SOLID TUMOR
Phase 1 • Sponsor: SynerGene Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC