Refractory Hodgkin lymphoma
Clinical trials for Refractory Hodgkin lymphoma explained in plain language.
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Experimental combo aims to tackle tough lymphomas
Disease control Recruiting nowThis early-phase trial is testing whether combining the immunotherapy drug nivolumab with the drug ASTX727 can help shrink or stabilize B-cell lymphomas that have returned or are not responding to treatment. About 32 adults with certain types of lymphoma will receive the combinat…
Matched conditions: REFRACTORY HODGKIN LYMPHOMA
Phase 1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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Smart blood test guides treatment for stubborn hodgkin lymphoma
Disease control Recruiting nowThis study tests a combination of the immunotherapy drug pembrolizumab and three chemotherapy drugs (GVD) in 38 adults whose Hodgkin lymphoma returned or did not respond to one prior treatment. A special blood test (ctDNA) is used to see how well the treatment is working and to g…
Matched conditions: REFRACTORY HODGKIN LYMPHOMA
Phase 2 • Sponsor: Michael Spinner, MD • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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New drug HCB301 enters early human trials for tough cancers
Disease control Recruiting nowThis early-phase trial is testing a new drug called HCB301 in 50 adults with advanced solid tumors or Hodgkin lymphoma that has come back or not responded to other treatments. The main goals are to check the drug's safety, find the right dose, and see if it shows any signs of shr…
Matched conditions: REFRACTORY HODGKIN LYMPHOMA
Phase 1 • Sponsor: FBD Biologics Limited • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New combo aims to tackle tough lymphomas
Disease control Recruiting nowThis phase II trial tests a combination of two drugs—pembrolizumab (an immunotherapy) and ATRA (a vitamin A derivative)—in 24 adults with relapsed or refractory Hodgkin lymphoma or B-Non-Hodgkin lymphoma. The goal is to see if the combo is safe and can shrink tumors. Participants…
Matched conditions: REFRACTORY HODGKIN LYMPHOMA
Phase 2 • Sponsor: Rita Assi • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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Radioactive antibody combo aims to beat back tough hodgkin lymphoma
Disease control Recruiting nowThis phase 2 trial tests a new approach for people with Hodgkin lymphoma that has not responded to treatment or has come back. It combines a radioactive antibody (yttrium-90 labeled anti-CD25) with standard BEAM chemotherapy before a stem cell transplant. The goal is to see if th…
Matched conditions: REFRACTORY HODGKIN LYMPHOMA
Phase 2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC