Refractory diffuse large B-cell lymphoma
Clinical trials for Refractory diffuse large B-cell lymphoma explained in plain language.
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New hope for tough blood cancers: experimental drug enters human testing
Disease control Stopped earlyThis early-stage study is testing an experimental drug called BGB-21447 in about 112 people with certain blood cancers (like lymphoma or leukemia) that have returned or not improved after prior treatments. The main goal is to find a safe dose and check for side effects, while als…
Matched conditions: REFRACTORY DIFFUSE LARGE B-CELL LYMPHOMA
Phase 1 • Sponsor: BeOne Medicines • Aim: Disease control
Last updated Jul 16, 2026 00:00 UTC
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New targeted therapy shows promise for Tough-to-Treat lymphomas
Disease control Stopped earlyThis study tests a drug called loncastuximab tesirine in adults with B-cell lymphomas that have returned or not responded to prior treatment. The drug works like a smart bomb, attaching to a marker on cancer cells and delivering chemotherapy directly to them. The main goal is to …
Matched conditions: REFRACTORY DIFFUSE LARGE B-CELL LYMPHOMA
Phase 2 • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New hope: drug may shield brain from CAR T-Cell therapy side effects
Disease control Stopped earlyThis study tested whether the drug anakinra could prevent severe brain inflammation (called ICANS) that sometimes happens after CAR T-cell therapy for certain types of lymphoma. The trial involved 23 adults whose lymphoma had returned or not responded to prior treatments. Researc…
Matched conditions: REFRACTORY DIFFUSE LARGE B-CELL LYMPHOMA
Phase 2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC