Refractory angina
Clinical trials for Refractory angina explained in plain language.
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Can a One-Time gene therapy relieve stubborn heart pain?
Cure Recruiting nowResearchers are testing XC001, an experimental gene therapy, in people with refractory angina, a type of chest pain caused by blocked heart arteries that persists despite medication and is not suitable for surgery or stenting. The trial delivers XC001 directly into the heart musc…
Matched conditions: REFRACTORY ANGINA
Phase 2 • Sponsor: XyloCor Therapeutics, Inc. • Aim: Cure
Last updated Sep 13, 2026 00:00 UTC
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Implantable device could offer new hope for patients with untreatable chest pain
Disease control Recruiting nowThis trial tests an implantable device called the Shockwave Reducer for people with severe, persistent chest pain (refractory angina) who cannot have standard treatments like stents or bypass surgery. About 380 participants will either receive the device or a sham procedure. The …
Matched conditions: REFRACTORY ANGINA
Sponsor: Shockwave Medical, Inc. • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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Could your own bone marrow ease incurable chest pain?
Symptom relief Recruiting nowThis study tests whether a single infusion of a patient's own bone marrow stem cells can reduce chest pain and improve quality of life for people with refractory angina—a severe form of chest pain that doesn't respond to standard treatments. About 110 participants will be randoml…
Matched conditions: REFRACTORY ANGINA
Phase 2 • Sponsor: Barts & The London NHS Trust • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC