Recurrent high-grade B-cell lymphoma
Clinical trials for Recurrent high-grade B-cell lymphoma explained in plain language.
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New combo therapy aims to boost immune attack on Hard-to-Treat lymphoma
Disease control PausedThis study tests whether adding an experimental drug (ST-067) to standard CAR T-cell therapy can safely and effectively treat adults with large B-cell lymphoma that has returned or not responded to prior treatments. About 33 participants will receive the combination to see if it …
Matched conditions: RECURRENT HIGH-GRADE B-CELL LYMPHOMA
Phase 1/2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Sep 13, 2026 00:00 UTC
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New drug cocktail aims to outsmart Hard-to-Treat lymphoma
Disease control OngoingThis phase 2 trial tests a combination of two drugs—TTI-622 and pembrolizumab (Keytruda)—in about 10 adults with diffuse large B-cell lymphoma that has come back or not responded to treatment. TTI-622 blocks a protein called CD47 that cancer cells use to hide from the immune syst…
Matched conditions: RECURRENT HIGH-GRADE B-CELL LYMPHOMA
Phase 2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC