PULMONARY ARTERIAL HYPERTENSION PAH
Clinical trials for PULMONARY ARTERIAL HYPERTENSION PAH explained in plain language.
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New drug may reverse lung artery damage in rare Heart-Lung condition
Disease control Not yet recruitingThis study looks at whether the drug sotatercept can help repair damaged blood vessels in the lungs of people with pulmonary arterial hypertension (PAH). Researchers will use special imaging techniques to see if the blood vessels become healthier over 9 months. The study plans to…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION PAH
Sponsor: Franz Rischard, DO • Aim: Disease control
Last updated May 26, 2026 05:08 UTC
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Stem cells aim to save tiniest lungs: new trial for premature babies with deadly blood pressure
Disease control Not yet recruitingThis early-stage study tests a single dose of PNEUMOSTEM® stem cells in 12 very premature babies with early pulmonary arterial hypertension (high blood pressure in the lungs). The goal is to see if it is safe and can improve breathing, reduce the need for oxygen and a breathing m…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION PAH
Phase: PHASE1 • Sponsor: Samsung Medical Center • Aim: Disease control
Last updated May 19, 2026 11:59 UTC
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New injection could boost heart function in lung disease patients
Disease control Not yet recruitingThis study tests whether adding an injectable medication called treprostinil to standard oral therapy can improve heart function in people with intermediate-risk pulmonary arterial hypertension (PAH). About 32 adults will receive the drug and be monitored for 3 months, with follo…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION PAH
Phase: PHASE2 • Sponsor: Shanghai Zhongshan Hospital • Aim: Disease control
Last updated May 18, 2026 12:10 UTC
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New study looks at Selexipag's Long-Term effects on rare lung condition
Disease control Not yet recruitingThis study looks at how well the oral medication selexipag works over the long term for people with a specific type of lung disease called schistosomiasis-associated pulmonary arterial hypertension. Researchers will compare patients who took selexipag with similar patients who di…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION PAH
Sponsor: Caio Júlio César dos Santos Fernandes • Aim: Disease control
Last updated May 15, 2026 11:53 UTC
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Triple therapy trial aims to ease rare lung disease
Disease control Not yet recruitingThis study tests whether a combination of three drugs (an endothelin receptor antagonist, a phosphodiesterase-5 inhibitor, and sotatercept) can improve blood flow in the lungs of people newly diagnosed with pulmonary arterial hypertension (PAH). 25 adults aged 18-70 will receive …
Matched conditions: PULMONARY ARTERIAL HYPERTENSION PAH
Phase: PHASE2 • Sponsor: Philipps University Marburg • Aim: Disease control
Last updated May 06, 2026 16:00 UTC
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PAH patients may ditch frequent inhaler for Once-a-Day pill
Symptom relief Not yet recruitingThis study follows adults with pulmonary arterial hypertension (PAH) whose doctor decides to switch them from an inhaled medication (iloprost, used several times a day) to an oral pill (selexipag). Researchers will measure changes in quality of life, treatment satisfaction, and h…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION PAH
Sponsor: University of Sao Paulo General Hospital • Aim: Symptom relief
Last updated May 26, 2026 05:05 UTC
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Toxins in hair and urine could unlock clues to lung disease
Knowledge-focused Not yet recruitingThis study looks at whether environmental toxins, drugs, and workplace exposures play a role in pulmonary hypertension (PAH), a rare and serious lung condition. Researchers will compare 150 newly diagnosed patients with PAH to those with another form of the disease (CTEPH). They …
Matched conditions: PULMONARY ARTERIAL HYPERTENSION PAH
Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 05:11 UTC
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New survey aims to better understand daily life with lung disease
Knowledge-focused Not yet recruitingThis study will create and test a new questionnaire to measure quality of life in people with pulmonary arterial hypertension (PAH) in China. Researchers will work with 300 patients to ensure the tool is accurate and useful. The goal is to help doctors and policymakers better und…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION PAH
Sponsor: Chinese Pulmonary Vascular Disease Research Group • Aim: Knowledge-focused
Last updated May 26, 2026 05:06 UTC
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New study to map how patients and caregivers search for pulmonary hypertension info
Knowledge-focused Not yet recruitingThis study uses a short questionnaire to find out where patients with pulmonary hypertension and their caregivers get health information, what topics they search for, and how satisfied they are with what they find. The goal is to improve communication and educational materials fo…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION PAH
Sponsor: University of Sao Paulo General Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC
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Scientists hunt for genes behind rare lung complication in liver shunt patients
Knowledge-focused Not yet recruitingThis study aims to find genetic changes in people who have both a rare liver blood vessel problem (congenital portosystemic shunt) and a serious lung condition called portopulmonary hypertension. Researchers will analyze DNA from 120 patients and their close family members to ide…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION PAH
Sponsor: Prof. Valérie Mc Lin • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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New PET scans to reveal if sotatercept repairs damaged arteries in PAH
Knowledge-focused Not yet recruitingThis pilot study will test whether the drug sotatercept can reduce scarring and remodeling of blood vessels in the lungs of 15 people with pulmonary arterial hypertension (PAH). Researchers will use special PET/CT scans to see changes in the arteries and right side of the heart o…
Matched conditions: PULMONARY ARTERIAL HYPERTENSION PAH
Phase: PHASE1, PHASE2 • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated May 11, 2026 20:39 UTC