PROSTATE CANCER METASTATIC

This study tests two drugs, pembrolizumab and lenvatinib, in 45 people with advanced neuroendocrine prostate cancer that has spread. The goal is to see if the combination can slow tumor growth. Treatment continues until the cancer worsens or side effects become too severe, for up…

This study tests an experimental drug called ARV-766, taken as a pill, for men with metastatic prostate cancer that has spread. The drug is given alone or with another medication (abiraterone). The goal is to see if it is safe and can shrink tumors or lower PSA levels. About 152 …

This study tests a new drug called ST101 in people with advanced solid tumors that cannot be removed by surgery or have spread. The goal is to find a safe dose and see if the drug can shrink tumors. About 125 adults with cancers like glioblastoma, melanoma, breast, or prostate ca…

This study looks at whether adding focused radiation or surgery to all visible cancer sites, on top of usual hormone therapy, can delay cancer growth in men whose prostate cancer has spread to just a few places (up to 5 spots). About 409 men took part. The goal is to see if this …

This study tests a new treatment called 177Lu-HTK03170 for men with a type of advanced prostate cancer that has stopped responding to hormone therapy. The treatment delivers radiation directly to cancer cells using a targeting molecule. The goal is to find a safe dose and see if …

This study checks if a special type of PET scan (PSMA PET) is more accurate than usual scans for seeing prostate cancer and how it responds to treatment. About 58 people with prostate cancer that is new or getting worse will take part. The goal is to see if this scan can better p…

This study looks at how two different prostate cancer medications, darolutamide and enzalutamide, affect thinking skills like memory and attention. About 111 men with advanced prostate cancer will take one of the two drugs and complete computer-based brain tests over time. The go…