PROGNOSTIC STAGE IIIA BREAST CANCER AJCC V8
Clinical trials for PROGNOSTIC STAGE IIIA BREAST CANCER AJCC V8 explained in plain language.
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New drug combo shrinks tumors before breast cancer surgery?
Disease control CompletedThis early-phase study tested the safety and best dose of two drugs, abemaciclib and niraparib, given together before surgery to people with hormone receptor-positive, HER2-negative breast cancer. The goal was to see if the combination could shrink tumors before surgery. Only 8 p…
Matched conditions: PROGNOSTIC STAGE IIIA BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated May 01, 2026 15:25 UTC
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New combo targets Hard-to-Treat cancers with gene mutations
Disease control CompletedThis early-phase study tested a new drug (AZD8186) combined with chemotherapy (docetaxel) in 23 adults with advanced solid tumors that have certain gene changes (PTEN or PIK3CB mutations). The main goal was to find the safest dose and understand side effects. Researchers hope thi…
Matched conditions: PROGNOSTIC STAGE IIIA BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 01, 2026 15:25 UTC
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Heart check: new study uses stress test to spot cancer treatment side effects
Knowledge-focused CompletedThis study looked at whether a special heart stress test (using an MRI and medication) can find early signs of heart damage in premenopausal women treated for breast cancer. 25 women who had already received chemotherapy or hormone therapy took part. The goal was to see if this t…
Matched conditions: PROGNOSTIC STAGE IIIA BREAST CANCER AJCC V8
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:50 UTC
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Cancer moonshot study banks tumors to unlock genetic secrets
Knowledge-focused CompletedThis study collected blood and tumor tissue from 64 people with advanced or treatment-resistant cancers. Researchers stored these samples to study how genes affect cancer growth and response to therapy. No new treatment was given; the goal was to build a resource for future resea…
Matched conditions: PROGNOSTIC STAGE IIIA BREAST CANCER AJCC V8
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Apr 29, 2026 15:02 UTC