PROGESTERONE RECEPTOR NEGATIVE

This study tested whether adding the drug trastuzumab to standard chemotherapy before surgery helps shrink breast tumors more effectively. It involved 92 women with early-stage breast cancer who had not received prior treatment. The main goals were to see if the combination was s…

This study tested whether giving two chemotherapy drugs (carboplatin and nab-paclitaxel) before surgery could effectively shrink tumors in patients with a hard-to-treat type of breast cancer called triple-negative breast cancer. The goal was to see if this approach could complete…

This early-phase study is testing the safety of combining a new cancer vaccine with an existing immunotherapy drug (pembrolizumab) in patients with advanced solid tumors that have spread and stopped responding to standard treatments. The vaccine is designed to train the immune sy…

This study is testing if adding a targeted drug called panitumumab to standard chemotherapy works better than chemotherapy alone before surgery for a fast-growing, hard-to-treat type of breast cancer. It aims to see which combination shrinks the tumor more effectively, potentiall…

This study is for patients with a specific, aggressive type of breast cancer (triple-negative, basal-like) where cancer cells remain after initial chemotherapy and surgery. It aims to find out which of two follow-up chemotherapy drugs—platinum-based drugs (cisplatin/carboplatin) …

This study tested whether the immunotherapy drug pembrolizumab could help control advanced inflammatory or triple-negative breast cancer in patients whose disease had already responded to or stabilized with chemotherapy. The trial involved 71 participants with these aggressive fo…

This early-stage trial is testing the safety and best doses of two different combinations of oral medications for people with recurrent endometrial, ovarian, or triple-negative breast cancer. The study combines an existing drug (olaparib) with one of two newer drugs (AZD2014 or A…

This study is testing whether two advanced imaging scans can predict how well chemotherapy will work for patients with triple-negative breast cancer before they have surgery. Researchers will compare these new scans to standard imaging to see which method better identifies patien…

This study is testing a special imaging scan to see if it can predict whether hormone therapy will work for patients with advanced breast cancer that has spread. The scan uses a radioactive form of estrogen to 'light up' cancer spots in the body. If successful, this scan could he…

This study aims to find the best way to help women understand their genetic cancer risk with less stress. It compares watching an online educational video alone to combining it with phone counseling sessions. The goal is to see which method helps participants feel less distressed…