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Can new scans predict chemo success in Triple-Negative breast cancer?

NCT ID NCT02744053

First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 33 times

Summary

This early-phase trial is testing whether two advanced imaging techniques—DCE-MRI and molecular breast imaging (MBI)—can accurately assess how triple-negative breast cancer tumors respond to chemotherapy. About 96 patients will undergo these scans before, during, and after treatment. The goal is to see if these imaging methods can predict which patients are responding well, potentially helping doctors tailor treatment earlier.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • MD Anderson League City

    Nassau Bay, Texas, 77058, United States

  • MD Anderson in Katy

    Houston, Texas, 77094, United States

  • MD Anderson in Sugar Land

    Sugar Land, Texas, 77478, United States

  • MD Anderson in The Woodlands

    The Woodlands, Texas, 77384, United States

  • Memorial Hermann Memorial City Medical Center

    Houston, Texas, 77024, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Technetium Tc-99m Sestamibi (imaging tracer)

What this could lead to

If successful, this could help doctors predict which triple-negative breast cancer patients are responding to chemotherapy, potentially guiding more personalized treatment.

What could go wrong

This is a very early (phase 1) imaging study with only 96 participants, so results may not apply broadly. It focuses on measuring response, not on improving outcomes directly.

Conditions

The condition(s) this trial relates to.

Her2-receptor negative breast cancer triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.