Prion diseases
Clinical trials for Prion diseases explained in plain language.
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Can a Long-Term watch program unlock the secrets of genetic prion disease?
Knowledge-focused Recruiting nowThis study follows adults with a family history of genetic prion disease to see how and when the condition first appears. Participants undergo regular check-ins and genetic testing over many years. The goal is to map the natural course of the disease and identify early markers th…
Matched conditions: PRION DISEASES
Sponsor: Brian Appleby • Aim: Knowledge-focused
Last updated Sep 18, 2026 00:00 UTC
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Scientists hunt for clues to predict rare brain disease before symptoms strike
Knowledge-focused Recruiting nowThis study aims to find biological markers in spinal fluid and blood that could signal the start of prion disease before symptoms appear. Researchers will follow 150 people who carry a genetic mutation for prion disease, along with family members and healthy volunteers. Participa…
Matched conditions: PRION DISEASES
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Aug 15, 2026 00:00 UTC