PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
Clinical trials for PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS explained in plain language.
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New drug shows promise in slowing progressive MS disability
Disease control CompletedThis study tested an experimental drug called SAR442168 against a placebo in 767 adults with primary progressive multiple sclerosis (PPMS). The goal was to see if the drug could delay worsening disability. Participants took the drug or placebo and were monitored for changes in mo…
Matched conditions: PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE3 • Sponsor: Sanofi • Aim: Disease control
Last updated May 26, 2026 04:31 UTC
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Cord blood cells injected into spine: a new hope for MS?
Disease control CompletedThis early-stage trial tested the safety of a new cell therapy called DUOC-01, made from donated umbilical cord blood, in 20 adults with primary progressive multiple sclerosis (PPMS). The cells were injected into the spinal fluid. The main goal was to check for side effects, not …
Matched conditions: PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE1 • Sponsor: Joanne Kurtzberg, MD • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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MS Drug's brain impact revealed in new analysis
Knowledge-focused CompletedThis study re-examines MRI scans from 732 people with primary-progressive multiple sclerosis who took part in the ORATORIO trial. Researchers want to see if ocrelizumab changes the choroid plexus, a brain area involved in inflammation. The goal is to better understand how the dru…
Matched conditions: PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
Sponsor: State University of New York at Buffalo • Aim: Knowledge-focused
Last updated May 26, 2026 04:43 UTC