Primary mediastinal large B-cell lymphoma
Clinical trials for Primary mediastinal large B-cell lymphoma explained in plain language.
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New dual-targeting CAR t therapy tested for hard-to-treat lymphoma
Disease control Stopped earlyThis early-phase study tested a new treatment called bbT369 for people with a type of blood cancer (B cell non-Hodgkin's lymphoma) that had come back or stopped responding to other treatments. The therapy uses a patient's own immune cells, which are modified to better recognize a…
Matched conditions: PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA
Phase 1 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:55 UTC
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Radiation after failed CAR t: tiny study halted early
Disease control Stopped earlyThis pilot study looked at whether radiation therapy could help people with lymphoma that did not respond to CAR T cell therapy. Only 3 participants were enrolled before the study was terminated. The main goal was to check safety and side effects of adding radiation shortly after…
Matched conditions: PRIMARY MEDIASTINAL LARGE B-CELL LYMPHOMA
Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC