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New Dual-Targeting CAR t therapy shows promise in early lymphoma trial

NCT ID NCT05169489

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 26 times

Summary

This early-phase study tested a new treatment called bbT369 for people with B cell non-Hodgkin's lymphoma that came back or didn't respond to standard therapy. The treatment uses a patient's own immune cells, modified to target two markers on cancer cells, plus a gene edit to improve effectiveness. The trial was terminated early, but results may still inform future research.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Colorado Blood Cancer Institute

    Denver, Colorado, 80218, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Sarah Cannon

    Nashville, Tennessee, 37203, United States

  • Stanford Cancer Institute

    Stanford, California, 94305, United States

Conditions

Explore the condition pages connected to this study.