Primary biliary cirrhosis
Clinical trials for Primary biliary cirrhosis explained in plain language.
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Can a new drug rescue the liver when standard therapy fails?
Disease control CompletedThis phase 2 trial is testing an experimental drug called HTD1801 (BUDCA) in adults with primary biliary cholangitis (PBC) who haven't responded adequately to standard treatment. The goal is to see if the drug can safely lower alkaline phosphatase (ALP) levels, a key marker of li…
Matched conditions: PRIMARY BILIARY CIRRHOSIS
Phase 2 • Sponsor: HighTide Therapeutics (Hong Kong) Limited • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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New MRI scan could replace liver biopsies
Diagnosis CompletedThis study tested how well a special MRI scan called LiverMultiScan can measure liver fat, iron, and scarring. 61 adults with various liver diseases had up to 6 scans on different machines. The goal was to see if the results are consistent when repeated on the same scanner or on …
Matched conditions: PRIMARY BILIARY CIRRHOSIS
Sponsor: Perspectum • Aim: Diagnosis
Last updated Jun 27, 2026 08:00 UTC
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Scientists hunt for genes behind rare liver disease
Knowledge-focused CompletedThis study looks at the genetic makeup of 1,500 people with Primary Biliary Cirrhosis (PBC), a rare liver disease, along with their close relatives. By comparing genes, researchers hope to find inherited factors that make someone more likely to develop PBC. The goal is to better …
Matched conditions: PRIMARY BILIARY CIRRHOSIS
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC