Premature birth

This trial tests a 12-week home-based program called SPRINT for infants aged 7-15 months who were born preterm or have a family history of conditions like ADHD, autism, or developmental delay. Parents use an app to guide daily play activities aimed at improving parenting skills a…

This study tests whether giving a daily probiotic mixture for 6 months can improve brain development in preterm infants who received antibiotics after birth. Researchers will enroll 116 babies and measure their developmental scores, gut bacteria changes, and inflammation markers.…

This trial compares two outpatient methods for sampling the lining of the uterus in women with abnormal uterine bleeding. The standard method uses a single-use Pipelle device, while the alternative uses a reusable manual vacuum aspiration (MVA) cannula, which is cheaper and requi…

Extremely premature babies face a high risk of bleeding in the brain during their first week of life. Researchers at two hospitals in Winnipeg are testing whether giving a baby's own mother's fresh breast milk as nasal drops for seven days can prevent this bleeding. The study pla…

Preterm birth often leaves children with lasting airway narrowing that causes breathlessness and limits exercise. Researchers are testing whether inhaled tiotropium, a drug already approved for older children with severe asthma, can improve lung function in preterm-born children …

This study tests whether a daily 15-minute massage for 14 days can reduce swelling (lymphedema) and improve comfort in 40 premature babies in the NICU. Half the infants will receive standard care, and the other half will also get gentle massage on their arms and legs. Researchers…

Researchers at Assiut University Children Hospital are tracking 100 preterm infants who need invasive mechanical ventilation in the neonatal intensive care unit. The study aims to identify which early factors predict prolonged ventilation, defined as more than 7 days or frequent …

This observational study follows 120 preterm infants admitted to the neonatal intensive care unit at Assiut University Children's Hospital. Researchers record clinical details, feeding methods, and growth measurements to see which factors predict postnatal growth failure, defined…

This study will test whether regularly checking pregnant women for hidden genital infections can reduce problems like preterm birth and low birth weight. 250 pregnant women will be split into two groups: one gets the extra screening and treatment, the other gets standard care. Th…

This study looks at whether recommending bed rest to pregnant women with a short cervix actually helps prevent preterm birth. Researchers will compare women who are told to rest with those who continue normal daily activities. The goal is to see if avoiding bed rest is just as sa…