PRADER-WILLI SYNDROME
Clinical trials for PRADER-WILLI SYNDROME explained in plain language.
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Growth hormone trial aims to boost muscle in Prader-Willi patients
Disease control CompletedThis completed Phase 3 study tested somatropin, a synthetic growth hormone, in 33 Japanese children and adults with Prader-Willi syndrome. The goal was to see if it safely improves body composition by increasing lean body mass and reducing fat. Participants were divided into thre…
Matched conditions: PRADER-WILLI SYNDROME
Phase: PHASE3 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 23, 2026 12:09 UTC
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New program aims to help Prader-Willi patients keep weight off
Disease control CompletedThis study tested a 5-week hospital program combining physical activity, nutrition advice, and education for 128 adults with Prader-Willi syndrome. The goal was to help patients stabilize or lose weight 6 months after leaving the hospital. The program focuses on changing daily ha…
Matched conditions: PRADER-WILLI SYNDROME
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 16, 2026 12:51 UTC
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Can a wakefulness drug beat daytime sleepiness in Prader-Willi syndrome?
Symptom relief CompletedThis phase 2 study tested whether pitolisant, a drug that promotes wakefulness, can safely reduce excessive daytime sleepiness in people with Prader-Willi syndrome. The trial enrolled 65 participants aged 6 to 65 and compared pitolisant to a placebo over 11 weeks, followed by an …
Matched conditions: PRADER-WILLI SYNDROME
Phase: PHASE2 • Sponsor: Harmony Biosciences Management, Inc. • Aim: Symptom relief
Last updated Jun 23, 2026 20:32 UTC
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Can a 'Love Hormone' spray tame Prader-Willi symptoms?
Symptom relief CompletedThis study tested whether oxytocin nasal spray, sometimes called the 'love hormone,' can improve behavior and eating problems in adults with Prader-Willi syndrome. Fifty participants received either oxytocin or a placebo daily or every three days for 28 days. Researchers measured…
Matched conditions: PRADER-WILLI SYNDROME
Phase: PHASE2, PHASE3 • Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated Jun 23, 2026 20:31 UTC
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Hormone study aims to unlock Prader-Willi feeding mystery
Knowledge-focused CompletedThis completed study looked at how appetite-regulating hormones change in infants with Prader-Willi syndrome during the first four years of life. Researchers collected blood samples from 215 infants to understand why they switch from poor feeding to severe overeating and obesity.…
Matched conditions: PRADER-WILLI SYNDROME
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:59 UTC