PMDD
Clinical trials for PMDD explained in plain language.
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Psilocybin microdoses put to the test for severe PMS mood symptoms
Symptom relief Not yet recruitingResearchers are testing whether a psilocybin-based drug called MLS101 is safe and tolerable for premenopausal women with premenstrual dysphoric disorder (PMDD), a condition that causes intense mood and physical symptoms before menstruation. The trial enrolls 32 women aged 18 to 5…
Matched conditions: PMDD
Phase 1 • Sponsor: MycoMedica Life Sciences PBC • Aim: Symptom relief
Last updated Sep 16, 2026 00:00 UTC
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New study tests sleep workshop as Drug-Free aid for PMDD
Symptom relief Not yet recruitingThis study tests a brief sleep-focused workshop for people with PMDD who have trouble sleeping. The workshop teaches about sleep and simple strategies to improve it. Researchers want to see if it's practical and helpful, using sleep diaries and activity watches. 72 participants w…
Matched conditions: PMDD
Sponsor: St. Joseph's Healthcare Hamilton • Aim: Symptom relief
Last updated Jun 27, 2026 12:25 UTC
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Could a tiny dose of LSD ease PMS? new study investigates
Symptom relief Not yet recruitingThis study tests whether very low doses of LSD (10 micrograms) taken daily or every other day during the premenstrual phase can reduce symptoms of severe PMS or PMDD. 150 women will be randomly assigned to LSD or placebo for three menstrual cycles. The goal is to see if LSD can s…
Matched conditions: PMDD
Sponsor: Friederike Holze • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Could a hyperactive immune system fuel PMDD? a new study investigates
Knowledge-focused Not yet recruitingThis study explores whether inflammation in the body is linked to the mood and psychological symptoms of Premenstrual Dysphoric Disorder (PMDD). Researchers will compare women with PMDD to healthy controls, tracking daily emotions and behaviors over two menstrual cycles and takin…
Matched conditions: PMDD
Sponsor: King's College London • Aim: Knowledge-focused
Last updated Aug 20, 2026 00:00 UTC