Perianal fistula
Clinical trials for Perianal fistula explained in plain language.
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Laser and the Body's own healing factors tested against stubborn anal fistulas
Cure Not yet recruitingResearchers are testing a combination treatment for people with recurrent cryptoglandular perianal fistula, a painful tunnel that keeps coming back after surgery. The study enrolls 25 adults who have had at least two failed fistula operations and have a seton drain in place for a…
Matched conditions: PERIANAL FISTULA
Sponsor: Complejo Hospitalario Universitario de Santiago • Aim: Cure
Last updated Sep 11, 2026 00:00 UTC
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Can a laser seal fistulas without major surgery?
Disease control Not yet recruitingThis trial tests whether a minimally invasive laser procedure can close low perianal fistulas as effectively as traditional open surgery. Adults with a primary low perianal fistula are randomly assigned to receive either laser closure or open fistulectomy. Researchers track heali…
Matched conditions: PERIANAL FISTULA
Sponsor: Assiut University • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Can a drug plus surgery heal Crohn's fistulas for good?
Disease control Not yet recruitingThis trial is testing whether combining the drug mirikizumab with a surgical procedure can help heal perianal fistulas in people with Crohn's disease. Participants will receive the drug through infusions and injections, along with two surgical steps to clean and close the fistula…
Matched conditions: PERIANAL FISTULA
Phase 4 • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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Laser vs. scalpel: which heals anal fistula faster?
Disease control Not yet recruitingThis study compares two ways to treat uncomplicated perianal fistula: conventional open surgery (fistulectomy) and a newer laser ablation technique. About 72 adults with a single, simple fistula tract will be randomly assigned to one of the two procedures. Researchers will track …
Matched conditions: PERIANAL FISTULA
Sponsor: PNS Hafeez - Naval Hospital • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
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Which surgery heals anal fistula best? new trial aims to find out
Disease control Not yet recruitingThis study compares three surgical techniques for treating a common type of anal fistula (a tunnel between the anal canal and skin). The trial will enroll 90 adults aged 18-65 who have not had fistula surgery before. Researchers will measure healing, recurrence, and impact on bow…
Matched conditions: PERIANAL FISTULA
Sponsor: Alexandria University • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Can MRI spot hidden fistula tracts? new study aims to find out
Diagnosis Not yet recruitingThis study will check how well MRI can find and map perianal fistulas before surgery. Thirty patients with suspected fistulas will get an MRI, and the results will be compared to what surgeons find during the operation. The goal is to see if MRI can help doctors plan better surge…
Matched conditions: PERIANAL FISTULA
Sponsor: Sohag University • Aim: Diagnosis
Last updated Jun 27, 2026 12:03 UTC