Patent ductus arteriosus
Clinical trials for Patent ductus arteriosus explained in plain language.
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Vitamin B1 shows promise for Kids' hearts after hole closure
Disease control CompletedThis study looked at whether giving thiamine (vitamin B1) for 28 days after a heart defect repair procedure helps children's hearts recover. The trial included 86 children aged 6 months to 18 years with certain heart defects. Researchers measured heart structure and function usin…
Matched conditions: PATENT DUCTUS ARTERIOSUS
Early phase 1 • Sponsor: Universitas Sumatera Utara • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New study aims to spot heart defects in newborns with simple blood test
Diagnosis CompletedThis completed study looked at 313 children to see if blood tests and advanced heart scans could help detect congenital heart disease earlier and predict which children might need surgery. Researchers compared children with heart defects to healthy controls using blood biomarkers…
Matched conditions: PATENT DUCTUS ARTERIOSUS
Sponsor: Lund University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:30 UTC
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Can a common painkiller given in the first 12 hours protect premature Babies' brains?
Prevention CompletedVery premature infants born before 28 weeks often have a blood vessel near the heart, called the patent ductus arteriosus, that stays open when it should close. A large opening can strain the heart and may affect brain development. In this trial, researchers use an early echocard…
Matched conditions: PATENT DUCTUS ARTERIOSUS
Phase 3 • Sponsor: Nantes University Hospital • Aim: Prevention
Last updated Sep 16, 2026 00:00 UTC
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Cartoon therapy cuts pain in young heart patients
Symptom relief CompletedThis study tested if combining cartoon-watching with nurse interaction could ease pain in children after heart surgery. 70 kids aged 3-7 took part; half got standard pain care, and the other half also watched cartoons with a nurse. The goal was to see if this fun, non-drug approa…
Matched conditions: PATENT DUCTUS ARTERIOSUS
Sponsor: Beijing Children's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Study questions routine ibuprofen for preemie heart condition
Knowledge-focused CompletedThis study looked at 541 premature babies with a heart condition called patent ductus arteriosus (PDA). Half received ibuprofen to close the vessel, while the other half got only supportive care like fluids or diuretics. Researchers compared closure rates and complications to see…
Matched conditions: PATENT DUCTUS ARTERIOSUS
Sponsor: Shengjing Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Light-Based monitoring could spare preemies from frequent heart scans
Knowledge-focused CompletedThis study looked at whether near-infrared spectroscopy (NIRS), a non-invasive light-based monitor, can detect changes in a common heart condition in very premature babies. Researchers measured oxygen levels in the brain and kidneys of 26 babies born before 32 weeks and compared …
Matched conditions: PATENT DUCTUS ARTERIOSUS
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC