Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Vitamin B1 shows promise for Kids' hearts after hole closure

NCT ID NCT06298344

Disease control Sponsor: Universitas Sumatera Utara Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving thiamine (vitamin B1) for 28 days after a heart defect repair procedure helps children's hearts recover. The trial included 86 children aged 6 months to 18 years with certain heart defects. Researchers measured heart structure and function using echocardiograms and blood tests to see if thiamine made a difference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

86 people

The number who actually took part.

Started

May 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

6 months to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients aged 6 months - 18 years. 2. Patients diagnosed with left to right shunt lesion CHD with heart failure based on ROSS or NYHA criteria. 3. Patients who will undergo intervention with transcatheter closure. Exclusion Criteria: 1. Patients who experienced acute infections before the procedure. 2. There are other heart defects that require surgery. 3. There is a hereditary, genetic disorder, syndrome or other chronic disease.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Atrial septal defect are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

atrial septal defect beriberi congenital cardiovascular shunt congenital heart disease patent ductus arteriosus Thiamine Deficiency ventricular septal defect

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Atrial septal defect Congenital heart disease Patent ductus arteriosus Thiamine deficiency Ventricular septal defect

Contacts and locations

Locations

  • RSUP H Adam Malik

    Medan, North Sumatera, 20136, Indonesia

More trials for these conditions

Other studies related to the condition(s) this trial covers.