PANCREATIC CARCINOMA

This study is for people whose advanced pancreatic cancer has spread and has a specific genetic change (BRCA1, BRCA2, or PALB2 mutation). It compares a new three-drug chemotherapy combination (NABPLAGEM) against the current standard two-drug combination. The goal is to see if add…

This study is testing how well and safely the diabetes medication glipizide works to lower high blood sugar in people with pancreatic cancer. Researchers are enrolling about 29 participants with active pancreatic cancer and high blood sugar to measure their glucose levels before …

This early-phase study is testing the safety of combining a new cancer vaccine with an existing immunotherapy drug (pembrolizumab) in patients with advanced solid tumors that have spread and stopped responding to standard treatments. The vaccine is designed to train the immune sy…

This study aims to find the best way to monitor pancreatic cysts, which can sometimes develop into cancer. It compares two different schedules of scans and tests: one with more frequent monitoring and one with less. The goal is to see which approach leads to better health outcome…

This early-phase study is testing a new radioactive tracer called 18F-αvβ6-BP to see if it can help doctors better locate cancers in the body using PET scans. The study involves 27 patients with breast, colorectal, lung, or pancreatic cancer. Researchers will inject the tracer an…

This study is testing whether pancreatic enzyme replacement therapy (PERT) can help people with advanced pancreatic cancer maintain their body weight while on chemotherapy. Researchers are comparing two different dosing schedules of the enzyme supplement pancrelipase. The main go…

This study is testing a web-based education tool called HOPE-Genomics to see if it helps cancer patients better understand their personal genetic test results and general cancer genomics. Researchers are comparing three different approaches to delivering this information to 465 p…

This study tests whether sending personalized education about genetic testing guidelines increases how many people get tested when they have a family history of pancreatic cancer. Researchers will work with 40 patients who have a close relative with pancreatic cancer to offer gen…