Overactive bladder (OAB)

This study is following 55 adults who have an implanted device that stimulates nerves to control overactive bladder. Researchers want to see if the device safely improves quality of life over the long term. Participants must have already tried other treatments without success.

This study tests whether low-intensity shockwave therapy can improve overactive bladder symptoms in women as well as or better than the standard drug solifenacin. Seventy women will be randomly assigned to receive either weekly shockwave sessions for 8 weeks or a daily pill for 1…

This study tests an online screening tool (website or app) to help people with frequent urination get diagnosed with overactive bladder earlier. About 1,000 adults who often need to urinate more than 7 times a day will use the tool and then see a specialist to confirm the diagnos…

This trial tests whether methenamine hippurate, a non-antibiotic antiseptic, can prevent urinary tract infections (UTIs) as effectively as standard antibiotics in women receiving BOTOX-A injections for overactive bladder. Participants will be randomly assigned to take either meth…

This study tests whether a small, portable nerve stimulation device worn at home can reduce urgent bathroom trips in people with overactive bladder. Sixty adults aged 18 to 65 will either use the device during daily life when they feel urgency or receive standard clinic-based ses…

This study is testing a new external device (Axonics ETS-02) to see if it is safe and works for people with overactive bladder or fecal incontinence. About 75 adults will wear the device for a short trial period. The goal is to check if the device stays attached and works properl…

This study tests a device called Tensi+ that uses mild electrical pulses to a nerve in the ankle to treat overactive bladder symptoms like sudden urges and frequent bathroom trips. About 60 adults with these symptoms will use the device at home for 12 weeks. The goal is to see if…

This trial tests a device called Cefar URO that sends mild electrical pulses to a nerve in the ankle, a method known as transcutaneous tibial nerve stimulation. The goal is to see if it reduces urge incontinence and other overactive bladder symptoms in adults, including those who…

This study tests a new method to deliver botulinum toxin (NT 201) directly into the bladder using the Vibe System for women with overactive bladder. The goal is to reduce daily urine leakage episodes. About 210 women aged 18-80 will participate, and the treatment is compared to a…

This study tests a non-implanted electrical stimulation device for women with overactive bladder (OAB). About 151 participants will use the device or take medication to see if the device safely reduces daily bathroom trips. The goal is to offer a non-surgical option for symptom r…

This study tests whether taking zinc supplements before a Botox injection can improve results for women with overactive bladder. 72 women will receive either zinc or a placebo pill for five days before their Botox treatment. Researchers will track how many need another injection …

This early study tests a new implantable device that senses bladder nerve signals and delivers stimulation to reduce sudden urges to urinate. Ten women with overactive bladder that hasn't improved with standard treatments will receive the device. The goal is to see if the device …

This study compares two medicines—tadalafil (a drug often used for erectile dysfunction) and solifenacin (a standard OAB treatment)—to see which works better for women with overactive bladder. About 480 women in Egypt will take one pill daily for 12 weeks. Researchers will track …

This study tests a device that uses radiofrequency energy inside the vagina to treat overactive bladder in women. It includes 202 women aged 22 to 80 who have had symptoms for at least 6 months. Half will get the real treatment and half a sham (fake) treatment to see if the devic…

This study compares two treatments for children with overactive bladder (OAB) of unknown cause: the standard medication oxybutynin and a nerve stimulation therapy (PTNS). About 124 children aged 6 to 16 will be randomly assigned to one treatment for three months. The goal is to s…

This study tests whether a prescription app called RiSolve can reduce overactive bladder symptoms in women better than standard educational handouts. About 596 women will use the app for 10 weeks or receive paper guides. Researchers will measure changes in symptom severity and qu…

This study looks at how Botox injections for overactive bladder affect the community of bacteria in the urinary tract of postmenopausal women. Researchers will collect urine samples before and after treatment to see if changes in the microbiome relate to treatment success or side…