OVERACTIVE BLADDER (OAB)

This study follows 55 adults with overactive bladder who use the Axonics SNM device, a nerve stimulator implanted to control urgent urination and frequency. Researchers will track safety and quality-of-life improvements over time. The goal is to confirm the device works well and …

This study tests an online screening tool (website or app) to help people with frequent urination get checked for overactive bladder (OAB) early. About 1,000 adults who pee more than 7 times a day will use the tool and, if flagged, see a specialist for a full diagnosis. The goal …

This study is testing a new external device (Axonics ETS-02) to see if it is safe and works for people with overactive bladder or fecal incontinence. About 75 adults will use the device for a short time. The main goals are to see if the device stays attached and works, and to che…

This study compares two treatments for children with overactive bladder (OAB) of unknown cause: the standard drug oxybutynin and a nerve stimulation method called PTNS. About 124 children aged 6 to 16 will be randomly assigned to one treatment for three months. The goal is to see…

This study tests whether taking zinc supplements before Botox injections can improve bladder control in women with overactive bladder. About 72 women will receive either zinc or a placebo for five days before their Botox treatment, then be followed for six months. The goal is to …

This study tests a non-implanted electrical stimulation device for women with overactive bladder (OAB). The goal is to see if the device safely reduces daily bathroom trips compared to medication. About 151 women aged 21 and older with OAB symptoms for over 6 months will particip…

This study looks at whether taking pumpkin seed oil extract can improve bladder function in people with overactive bladder. Researchers at Northwestern University will give 40 participants the supplement for 12 weeks and track changes using surveys. The goal is to see if this nat…

This study tests a device that uses radiofrequency energy inside the vagina to treat overactive bladder in women. Researchers want to see if it reduces sudden urine leaks better than a sham (fake) treatment. About 202 women aged 22 to 80 with at least 6 months of symptoms will re…

This early study tests a personalized nerve-stimulating device in 10 women with overactive bladder that hasn't improved with standard treatments. The device is implanted near the sacral nerve to sense bladder activity and deliver stimulation when needed. The goal is to see if it …

This study compares two once-daily pills—tadalafil and solifenacin—to see which better controls overactive bladder symptoms in women. About 480 women aged 18 to 75 with symptoms for at least 3 months will participate. Over 12 weeks, they will track their bathroom habits and repor…

This study tests a prescription smartphone app called RiSolve to see if it can reduce overactive bladder symptoms in women. About 596 women with bothersome bladder issues will either use the app or receive standard educational handouts for 8 weeks. The goal is to improve symptoms…

This study tests whether low-intensity shockwave therapy can ease overactive bladder symptoms in women as well as a standard daily medication. Seventy women will receive either weekly shockwave sessions for 8 weeks or a daily pill for 12 months. The goal is to see which approach …

This study looks at how the bacteria in the bladder and urinary tract change in postmenopausal women who receive Botox injections for overactive bladder. Researchers will collect urine samples before and four weeks after treatment to compare bacteria from samples taken at home ve…