OVARIAN NEOPLASMS

This early-stage study is testing a new experimental drug called SGN-MesoC2 in people with advanced solid tumors that have stopped responding to standard treatments. The main goal is to find the safest dose and understand how the drug behaves in the body. The study includes 19 pa…

This study tested whether taking a daily pill called niraparib could help keep advanced ovarian cancer from returning after successful chemotherapy. It involved 733 women whose cancer had responded well to initial platinum-based chemotherapy. Participants were randomly assigned t…

This study is testing an experimental drug called disitamab vedotin in people with advanced or metastatic cancers that have spread and express a marker called HER2. The trial includes 120 adults with head and neck, lung, ovarian, or endometrial cancer who have already tried other…

This large, late-stage study is testing whether adding two newer drugs (dostarlimab and niraparib) to standard chemotherapy works better than standard care alone for women newly diagnosed with advanced ovarian cancer. The main goal is to see if the new combination can keep the ca…

This is a first-in-human study to find a safe dose and see how the body processes a new oral drug called ATV-1601. It is being tested in adults with advanced solid tumors, including certain breast cancers, that have a specific genetic change called an AKT1 E17K mutation. The main…

This study is testing whether a personalized vaccine called Vigil can help women with advanced ovarian cancer stay cancer-free longer after their initial surgery and chemotherapy. The vaccine is made from each patient's own tumor cells and is given as a series of injections. Rese…

This study aims to understand the genetic causes of cancer that run in families. Researchers are collecting blood or saliva samples from patients with certain cancers and their relatives to build a DNA bank. The goal is to identify genetic patterns that increase cancer risk, whic…