OSTEOPOROSIS, POSTMENOPAUSAL

This study tests two different ways of giving two osteoporosis drugs (romosozumab and denosumab) over two years. One group gets a repeating 6-month cycle of each drug, while the other gets 12 months of one drug followed by 12 months of the other. The goal is to see which schedule…

This study compares two FDA-approved medication regimens to see which works better for improving bone density in postmenopausal women with osteoporosis who are at high risk of fractures. About 50 women aged 45 and older will take one of the two drug combinations for 12 months. Th…

This study looks at how mechanical loading, like standing or vibration, changes nerve reflexes in postmenopausal women with and without osteoporosis. Researchers want to understand if weak bones alter these reflexes, which could explain how weight-bearing exercise helps bones. Th…

This study aims to understand how the osteoporosis drug romosozumab changes bone cells over time. Researchers will study 16 postmenopausal women who are already prescribed this medication. The goal is to see if the drug increases early bone-forming cells but not later ones, helpi…

This study looks at whether blood tests called Bone Turnover Markers (BTMs) can quickly show if osteoporosis medication is working in postmenopausal women. Currently, doctors use DEXA scans to check bone density, but these change slowly. BTMs might show results in just 3 to 6 mon…