OPIOID

This study tests a smartphone game called MedSMA℞T Mobile, designed to help parents and their teenage children learn how to use, store, and dispose of opioids safely. About 244 families will play the game for 30 minutes and complete surveys over 9 months. The goal is to see if th…

Researchers at Stanford University are studying whether suzetrigine, a non-opioid pain medicine, can reduce the amount of oxycodone adults need after tonsillectomy or similar throat surgery. The trial enrolls 58 adults scheduled for these procedures. Participants receive suzetrig…

This study compares standard fentanyl pain medicine to an opioid-free mix of acetaminophen, ibuprofen, ketamine, and dexamethasone in 64 children aged 5-10 with mild to moderate sleep apnea undergoing tonsil surgery. The goal is to see if the opioid-free option controls pain just…

This trial investigates whether activating the body's opioid system with a single dose of morphine influences stress responses and social behavior differently in men and women. It also examines how early life stress may modulate these effects. Healthy adults aged 18-40 will recei…

This study will track opioid use in 35 adults undergoing thoracotomy (chest surgery) to see how much pain medication they need and what factors affect their pain. Researchers will also look at how opioid use relates to complications and hospital stay length. The goal is to better…

This study tests whether giving dentists personalized reports comparing their opioid prescribing to others, along with educational materials, can reduce opioid use for dental pain. About 3,500 dentists in British Columbia will be randomly assigned to receive these materials early…

This study looks at how opioid painkillers affect the success of immunotherapy in 100 people with advanced lung cancer who have moderate to severe pain. Researchers want to see if better pain control helps immunotherapy work better, and whether opioids themselves change the treat…