OPEN HEART SURGERY
Clinical trials for OPEN HEART SURGERY explained in plain language.
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New drug may shield kidneys during heart surgery
Disease control CompletedThis study tested a drug called ilofotase alfa in 271 adults at risk for kidney damage after open heart surgery. Participants received two doses of the drug or a placebo through a vein. The goal was to see if the drug could keep kidneys working better after surgery.
Matched conditions: OPEN HEART SURGERY
Phase: PHASE2 • Sponsor: AM-Pharma • Aim: Disease control
Last updated May 26, 2026 11:14 UTC
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Heart drug showdown: which works better during bypass surgery?
Disease control CompletedThis study compared two drugs, levosimendan and adrenaline, given during heart bypass surgery to 60 patients with weak hearts (ejection fraction 30-40%). The goal was to see which drug better supports heart function during and right after surgery. Researchers measured heart pumpi…
Matched conditions: OPEN HEART SURGERY
Phase: NA • Sponsor: Assiut University • Aim: Disease control
Last updated May 18, 2026 11:58 UTC
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Pre-Surgery video eases ICU jitters for heart patients
Symptom relief CompletedThis study looked at whether showing patients a video about what to expect in the intensive care unit (ICU) before open-heart surgery could lower their anxiety and improve their ICU experience. 110 adults scheduled for planned open-heart surgery took part. The goal was to see if …
Matched conditions: OPEN HEART SURGERY
Phase: NA • Sponsor: Zeynep Turak • Aim: Symptom relief
Last updated May 26, 2026 11:15 UTC
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New pain block may speed recovery after Open-Heart surgery
Symptom relief CompletedThis study tested a new type of nerve block called SPSIPB to see if it reduces pain and helps people recover faster after open-heart surgery. 70 adults having elective open-heart surgery were randomly assigned to receive either the SPSIPB or standard pain management. The main goa…
Matched conditions: OPEN HEART SURGERY
Phase: NA • Sponsor: Bursa City Hospital • Aim: Symptom relief
Last updated May 12, 2026 13:40 UTC
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New nerve block eases pain after Open-Heart surgery
Symptom relief CompletedThis study tested whether a nerve block called erector spinae plane block (ESPB) can improve pain control and recovery after open-heart surgery. 66 adults were randomly assigned to receive either the nerve block or standard intravenous painkillers. Researchers measured pain score…
Matched conditions: OPEN HEART SURGERY
Phase: NA • Sponsor: Karadeniz Technical University • Aim: Symptom relief
Last updated Apr 26, 2026 19:35 UTC
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New study reveals best way to drain chest after heart surgery
Knowledge-focused CompletedThis study looked at two methods of draining blood and fluid from the chest after heart surgery. Researchers reviewed records of 250 adults from three hospitals to see if a special active drainage system leads to fewer complications than standard drainage. The goal is to find out…
Matched conditions: OPEN HEART SURGERY
Sponsor: Kasr El Aini Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 11:15 UTC
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Eye ultrasound may help track brain pressure during heart bypass surgery
Knowledge-focused CompletedThis study looked at whether ultrasound measurements of the optic nerve sheath (the lining around the eye nerve) can detect changes in brain pressure during open-heart surgery that uses a heart-lung machine. Researchers measured this in 40 adults undergoing elective heart surgery…
Matched conditions: OPEN HEART SURGERY
Sponsor: Medipol University • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC