OBESE
Clinical trials for OBESE explained in plain language.
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New obesity drug HM15275 shows promise in Mid-Stage trial
Disease control OngoingThis study tests a new drug called HM15275 to help people with obesity lose weight. It involves 267 adults who are obese or overweight but do not have diabetes. Participants receive either the drug or a placebo for 36 weeks to see how much weight they lose and if the drug is safe…
Matched conditions: OBESE
Phase: PHASE2 • Sponsor: Hanmi Pharmaceutical Company Limited • Aim: Disease control
Last updated May 26, 2026 04:06 UTC
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New pill shows promise for diabetes and weight loss in early trial
Disease control OngoingThis study tests a new medication called aleniglipron in adults with type 2 diabetes who are also overweight or have obesity. The main goal is to check if the drug is safe and tolerable at different doses. Researchers will also measure changes in body weight and blood sugar level…
Matched conditions: OBESE
Phase: PHASE2 • Sponsor: Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics • Aim: Disease control
Last updated May 18, 2026 12:04 UTC
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Breakfast brain boost: study probes Food's effect on young minds
Knowledge-focused OngoingThis study looks at how what a child eats in the morning influences their thinking and brain function. Researchers will test 151 children aged 9-10, including those with obesity, using psychological assessments and brain scans. The goal is to understand the link between morning n…
Matched conditions: OBESE
Phase: NA • Sponsor: Arkansas Children's Hospital Research Institute • Aim: Knowledge-focused
Last updated May 26, 2026 04:10 UTC
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Olive Oil's secret weapon: polyphenols may boost heart health
Knowledge-focused OngoingThis study looks at whether two types of olive oil can change risk factors for heart disease, such as cholesterol levels, inflammation, and gene activity. Researchers will test blood samples from 44 healthy adults of different body weights after they consume the oils. The goal is…
Matched conditions: OBESE
Phase: NA • Sponsor: University of California, Davis • Aim: Knowledge-focused
Last updated May 26, 2026 04:06 UTC
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Could a Weight-Loss drug boost brain health? new study investigates
Knowledge-focused TerminatedThis study looks at whether liraglutide (Saxenda®), a drug used for weight loss, can increase a brain-health marker called BDNF in people with multiple sclerosis, long-COVID, or leukemia (in remission) who also have obesity and memory or thinking problems. About 30 participants w…
Matched conditions: OBESE
Phase: EARLY_PHASE1 • Sponsor: University of Chicago • Aim: Knowledge-focused
Last updated May 22, 2026 14:02 UTC
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Can a healthy lifestyle reprogram sperm? new study investigates.
Knowledge-focused OngoingThis study looks at whether diet and exercise can improve the genetic markers in sperm of overweight, inactive Hispanic men. Researchers will compare sperm samples from 100 men before and after a 12-week program of diet changes, exercise, or both. The goal is to see if lifestyle …
Matched conditions: OBESE
Phase: NA • Sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center • Aim: Knowledge-focused
Last updated May 19, 2026 11:47 UTC
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Gut sugar test may forecast surgery success
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to see if how the small intestine absorbs sugar can predict how much weight people lose after bariatric surgery. Researchers will compare obese patients scheduled for surgery with lean individuals. They will also check for gene changes that might affect sugar abso…
Matched conditions: OBESE
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 08, 2026 12:03 UTC