NEURO-DEGENERATIVE DISEASE

This study tests a drug called cobimetinib in children and adults with histiocytic disorders like Langerhans cell histiocytosis that have not responded to standard treatment. Cobimetinib works by blocking a faulty growth signal inside cells. The goal is to shrink tumors and contr…

This study tests whether custom 3D-printed cutlery handles can help people with neurodegenerative diseases eat more independently. Researchers will give 75 patients in rehabilitation care handles tailored to their grip. They will measure changes in eating ability and food intake …

This study uses non-invasive eye scans (OCT and OCTA) to look for changes in the retina that might be linked to brain diseases like Alzheimer's, Parkinson's, and multiple sclerosis. Researchers aim to find early markers that could help diagnose or track these conditions. The stud…

This study looks at how stroke changes the way the brain handles walking while doing another task, like listening or navigating. Researchers will monitor brain activity in 50 stroke survivors as they walk on different paths and respond to sounds. The goal is to better understand …

This study will follow 1,000,000 adults aged 18 and older for the rest of their lives. Researchers will collect health measurements and track who develops diseases, becomes frail, or dies. The goal is to find which tests best predict how well people age, so doctors can one day of…

This study follows 20 people with a rare nerve disease called CMT4J for up to 2 years. Researchers will track symptoms and health changes to better understand how the disease progresses. The goal is to find better ways to measure the disease, which could help design future treatm…

This study looks at the experiences of extended family members—like grandchildren, siblings, and nieces/nephews—who care for a loved one with dementia. Researchers want to learn what challenges these caregivers face, what services they use, and what barriers prevent them from get…