MYOSITIS

This early-stage study tests a one-time treatment made from donor immune cells that are gene-edited to target and destroy faulty immune cells causing disease. It is for 80 adults with severe lupus, scleroderma, or myositis that have not responded to standard therapies. The main g…

This study is testing a new treatment for people with certain autoimmune diseases (rheumatoid arthritis, Sjögren's disease, myositis, or scleroderma) that have not responded to standard therapies. The treatment combines a natural killer cell therapy called AlloNK with the drug ri…

This study tests an experimental drug called dazukibart for people with active dermatomyositis or polymyositis, rare diseases that cause muscle weakness and sometimes skin rash. About 318 adults will receive either the drug or a placebo by IV every 4 weeks for 48 weeks, while con…

This study is testing a device called mScan that uses a tiny, painless electrical current to measure muscle health. It takes about 6 seconds and is held against the skin. Researchers want to see if it can give similar results to an MRI, which is slower and more expensive. The goa…

This study is creating a large collection of blood samples and medical information from 3000 people with autoimmune diseases like lupus, scleroderma, and myositis. The goal is to help researchers find new markers and develop better treatments. Participants will not receive any ex…

This study asks people with rare myositis diseases (like dermatomyositis or inclusion body myositis) and their caregivers what they think researchers should focus on. Through online surveys and forums, the goal is to create a list of patient-driven research priorities. The study …

This study looks at whether certain environmental exposures—like infections, stress, or sun exposure—are more common in people with anti-synthetase syndrome (a type of myositis with lung involvement) compared to other myositis patients and healthy volunteers. Researchers will col…