MYELOFIBROSIS，MF
Clinical trials for MYELOFIBROSIS，MF explained in plain language.
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New hope for myelofibrosis patients: drug combo targets spleen swelling
Disease control CompletedThis study tested a drug called navitoclax, either alone or added to the standard treatment ruxolitinib, in 191 people with a bone marrow cancer called myelofibrosis. The main goal was to see if the treatment could shrink an enlarged spleen by at least 35% after 24 weeks. The stu…
Matched conditions: MYELOFIBROSIS，MF
Phase: PHASE2 • Sponsor: AbbVie • Aim: Disease control
Last updated May 19, 2026 12:01 UTC
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New combo aims to shrink enlarged spleens in bone marrow cancer
Disease control CompletedThis study tests whether adding the experimental drug navitoclax to the standard drug ruxolitinib works better than ruxolitinib alone for people with myelofibrosis, a type of bone marrow cancer. About 252 adults with myelofibrosis took part. The main goal was to see if the combo …
Matched conditions: MYELOFIBROSIS，MF
Phase: PHASE3 • Sponsor: AbbVie • Aim: Disease control
Last updated May 18, 2026 12:07 UTC
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New pill shows promise for rare bone marrow cancers in early trial
Disease control CompletedThis early-phase study tested a new drug called flonoltinib maleate in 31 people with myeloproliferative neoplasms (MPNs), a group of bone marrow cancers that includes myelofibrosis. The main goal was to check the drug's safety and find the right dose. The drug targets specific p…
Matched conditions: MYELOFIBROSIS，MF
Phase: PHASE1, PHASE2 • Sponsor: Chengdu Zenitar Biomedical Technology Co., Ltd • Aim: Disease control
Last updated May 18, 2026 12:04 UTC