Myelin oligodendrocyte glycoprotein antibody-associated disease
Clinical trials for Myelin oligodendrocyte glycoprotein antibody-associated disease explained in plain language.
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Can CRISPR-Edited cells stop autoimmune attacks on the brain?
Cure Not yet recruitingThis trial tests a therapy called CTX112 in adults with severe neurologic autoimmune diseases, including progressive multiple sclerosis, neuromyelitis optica, and stiff-person syndrome. CTX112 uses donor T cells edited with CRISPR to target and deplete B cells, which are thought …
Matched conditions: MYELIN OLIGODENDROCYTE GLYCOPROTEIN ANTIBODY-ASSOCIATED DISEASE
Phase 1/2 • Sponsor: CRISPR Therapeutics • Aim: Cure
Last updated Sep 11, 2026 00:00 UTC
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MOGAD mystery: do headaches signal more?
Knowledge-focused Not yet recruitingThis study aims to find out how often headaches happen in people with MOGAD, a rare disease that affects the brain and nerves. Researchers will look at the medical records of 25 adults and also follow them forward in time to describe headache patterns. The goal is to better under…
Matched conditions: MYELIN OLIGODENDROCYTE GLYCOPROTEIN ANTIBODY-ASSOCIATED DISEASE
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Massive Real-World study to track brain and nerve autoimmune disorders
Knowledge-focused Not yet recruitingThis study will follow 1,550 adults with various neurological autoimmune diseases—like multiple sclerosis, myasthenia gravis, and autoimmune encephalitis—to see how these conditions progress and respond to treatments in everyday medical practice. Researchers will measure disabili…
Matched conditions: MYELIN OLIGODENDROCYTE GLYCOPROTEIN ANTIBODY-ASSOCIATED DISEASE
Sponsor: Tongji Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC