Muscle atrophy

This early-phase trial tests a new drug called IMM01-STEM, made from stem cell secretions, in 28 people with muscle wasting due to knee osteoarthritis. The main goal is to check safety and find the right dose. Participants receive injections and are monitored for side effects ove…

This study tests whether low-load arm exercises combined with inflatable cuffs that briefly restrict blood flow can improve muscle size and small blood vessel health in older adults. Participants aged 50 and older are randomly assigned to exercise with the cuffs, exercise without…

This study tested whether a single infusion of zoledronic acid can prevent bone and muscle loss in adults aged 35 and older who are undergoing bariatric surgery. Fifty-nine participants were randomly assigned to receive either the drug or a placebo. The main goal was to measure c…

This study looked at whether adding robot-assisted walking training to stationary cycling helps people who recently had a stroke and are losing muscle. 53 participants did either cycling alone or cycling plus robot walking for 4 weeks. The goal was to see if the combination impro…

Researchers at the University of Malaya are studying how COVID-19 affects muscle loss and strength in critically ill patients. They will compare quadricep muscle thickness and cross-sectional area, along with handgrip and knee extension strength, between COVID-19 and non-COVID-19…

This study looked at how eating more or fewer calories affects muscle protein production and muscle size in healthy middle-aged adults during a short period of leg immobilization. Twenty-three participants were monitored under different energy intake conditions. The goal is to un…